Leprecan-Like 4 antibody (AA 1-100)

Catalog No. ABIN5675686

Product Details anti-Leprecan-Like 4 Antibody

Target: Leprecan-Like 4 (LEPREL4)

Binding Specificity: AA 1-100

Reactivity: Rat, Macaque

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Leprecan-Like 4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Cross-Reactivity: Macaque, Rat

Predicted Reactivity: Human,Mouse,Dog,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SC65

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Leprecan-Like 4

Target: Leprecan-Like 4 (LEPREL4)

Alternative Name: SC65 (LEPREL4 Products)

Synonyms: NO55 antibody, NOL55 antibody, SC65 antibody, 1110036O03Rik antibody, AI413214 antibody, Sc65 antibody, prolyl 3-hydroxylase family member 4 (non-enzymatic) antibody, P3H4 antibody, P3h4 antibody

Background:

Synonyms: Leprecan-like protein 4, Leprel4, NOL55, Nucleolar autoantigen 55 kDa, Nucleolar autoantigen No55, SC 65, SC65_HUMAN, Synaptonemal complex protein SC65.

Background: Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linking of collagen fibrils. Required for normal bone density and normal skin stability via its role in hydroxylation of lysine residues in collagen alpha chains and in collagen fibril assembly.

Gene ID: 10609

UniProt: Q92791