RAB11FIP2 antibody (AA 331-430) (Biotin)

Catalog No. ABIN5675672

Product Details anti-RAB11FIP2 Antibody (Biotin)

Target: RAB11FIP2 (RAB11 Family Interacting Protein 2 (Class I) (RAB11FIP2))

Binding Specificity: AA 331-430

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB11FIP2 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Pig,Horse,Chicken,Cat,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RAB11-FIP2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for RAB11FIP2

Target: RAB11FIP2 (RAB11 Family Interacting Protein 2 (Class I) (RAB11FIP2))

Alternative Name: RAB11-FIP2 (RAB11FIP2 Products)

Synonyms: RGD1308538 antibody, Rab11-FIP2 antibody, nRip11 antibody, 4930470G04Rik antibody, A830046J09Rik antibody, AW558126 antibody, Nrip11 antibody, RAB11 family interacting protein 2 antibody, RAB11 family interacting protein 2 (class I) antibody, Rab11fip2 antibody, RAB11FIP2 antibody

Background:

Synonyms: RAB11FIP2,KIAA0941, NRip11, RAB11 family interacting protein 2 (class I), Rab11 family-interacting protein 2, RAB11 FIP2 long isoform, Rab11-FIP2, RFIP2, RFIP2_HUMAN.

Background: A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity.

Gene ID: 22841

UniProt: Q7L804

Pathways: Hormone Transport, Carbohydrate Homeostasis