SWAP70 antibody (AA 131-230)

Catalog No. ABIN5675636

Product Details anti-SWAP70 Antibody

Target: SWAP70 (SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))

Binding Specificity: AA 131-230

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SWAP70 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SWAP70

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for SWAP70

Target: SWAP70 (SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))

Alternative Name: SWAP70 (SWAP70 Products)

Synonyms: SWAP-70 antibody, 70kDa antibody, AV235546 antibody, HSPC321 antibody, swap70b antibody, zgc:63599 antibody, switching B-cell complex subunit SWAP70 antibody, SWA-70 protein antibody, SWAP switching B-cell complex 70 antibody, SWAP switching B-cell complex 70kDa subunit antibody, switching B-cell complex subunit SWAP70a antibody, SWAP70 antibody, Swap70 antibody, swap70 antibody, swap70a antibody

Background:

Synonyms: Switch-associated protein 70, SWAP70, SWAP70, KIAA0640, HSPC321

Background: Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.

Gene ID: 23075

UniProt: Q9UH65

Pathways: Production of Molecular Mediator of Immune Response