ADC antibody (AA 51-150)

Catalog No. ABIN5675428

Product Details anti-ADC Antibody

Target: ADC (Arginine Decarboxylase (ADC))

Binding Specificity: AA 51-150

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADC antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), ELISA, Immunocytochemistry (ICC)

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ODCp

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for ADC

Target: ADC (Arginine Decarboxylase (ADC))

Alternative Name: ODCp (ADC Products)

Synonyms: MGC134604 antibody, azi2 antibody, odc2 antibody, odc-p antibody, odc1l antibody, xodc2 antibody, ADC antibody, AZI2 antibody, ODC-p antibody, ODC1L antibody, 4933429I20Rik antibody, AZIN2 antibody, Azi2 antibody, B930082O19 antibody, Odcp antibody, RGD1564776 antibody, odc1-b antibody, arginine decarboxylase antibody, antizyme inhibitor 2 antibody, biosynthetic arginine decarboxylase SpeA antibody, biosynthetic arginine decarboxylase SpeA (ADC) antibody, pyruvoyl-dependent arginine decarboxylase antibody, antizyme inhibitor 2 S homeolog antibody, AZIN2 antibody, azin2 antibody, adc antibody, speA antibody, Mrub_2839 antibody, MMAH_RS09440 antibody, Arnit_1968 antibody, Mesil_3114 antibody, Trad_0080 antibody, Spirs_3255 antibody, LOC100233080 antibody, Azin2 antibody, azin2.S antibody

Background:

Synonyms: Antizyme inhibitor 2, AZIN2, Arginine decarboxylase, ADC, ARGDC, Ornithine decarboxylase-like protein, ODC-like protein, ornithine decarboxylase paralog, ODC-p, AZIN2, ADC, KIAA1945, ODCP

Background: Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding (PubMed:17900240). Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production (PubMed:17900240). Participates in the morphological integrity of the trans-Golgi network (TGN) and functions as a regulator of intracellular secretory vesicle trafficking (PubMed:20188728).

Gene ID: 113451

UniProt: Q96A70