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tau antibody

Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Mouse Monoclonal 12F4 unconjugated
Catalog No. ABIN5675317
  • Target See all tau Antibodies
    tau (tau Protein)
    Reactivity
    • 579
    • 541
    • 538
    • 42
    • 28
    • 27
    • 18
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 685
    • 37
    • 3
    • 2
    Mouse
    Clonality
    • 662
    • 64
    • 1
    Monoclonal
    Conjugate
    • 238
    • 40
    • 31
    • 29
    • 24
    • 24
    • 24
    • 24
    • 24
    • 24
    • 24
    • 24
    • 24
    • 22
    • 22
    • 15
    • 15
    • 15
    • 15
    • 15
    • 15
    • 12
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    This tau antibody is un-conjugated
    Application
    • 570
    • 272
    • 263
    • 214
    • 92
    • 85
    • 68
    • 59
    • 54
    • 37
    • 34
    • 17
    • 12
    • 12
    • 12
    • 9
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Tau
    Clone
    12F4
    Isotype
    IgG
    Top Product
    Discover our top product tau Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    tau (tau Protein)
    Alternative Name
    Tau (tau Products)
    Synonyms
    DDPAC antibody, FTDP-17 antibody, MAPTL antibody, MSTD antibody, MTBT1 antibody, MTBT2 antibody, PPND antibody, TAU antibody, tau antibody, PHF-tau antibody, microtubule associated protein tau antibody, MAPT antibody
    Background

    Synonyms: MAPT, Microtuble-associted protein Tau, AI413597, AW045860, DDPAC, Disinhibition dementia parkinsonism amyotrophy complex, FLJ31424, FTDP 17, FTDP17, G Protein beta 1 gamma 2 subunit interacting factor 1, G protein beta1/gamma2 subunit interacting factor 1, MAPTL, MGC134287, MGC138549, MGC156663, Microtubule associated protein tau isoform 4, MSTD, Mtapt, MTBT1, MTBT2, Neurofibrillary tangle protein, Paired helical filament tau, PHF tau, PHF-tau, PPND, pTau, RNPTAU, Tauopathy and respiratory failure, included, TAU_HUMAN.

    Background: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

    Gene ID
    4137
    UniProt
    P10636
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