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MED12 antibody (AA 251-350)

MED12 Reactivity: Mouse, Rat ELISA, WB, IF (cc), IF (p), IHC (p), ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5675220
  • Target See all MED12 Antibodies
    MED12 (Mediator Complex Subunit 12 (MED12))
    Binding Specificity
    • 14
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 251-350
    Reactivity
    • 28
    • 24
    • 16
    • 1
    • 1
    • 1
    • 1
    Mouse, Rat
    Host
    • 38
    • 1
    • 1
    Rabbit
    Clonality
    • 39
    • 1
    Polyclonal
    Conjugate
    • 16
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MED12 antibody is un-conjugated
    Application
    • 24
    • 14
    • 12
    • 12
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Mouse, Rat
    Predicted Reactivity
    Human,Cow,Sheep,Pig,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MED12/Trap230
    Isotype
    IgG
    Top Product
    Discover our top product MED12 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    MED12 (Mediator Complex Subunit 12 (MED12))
    Alternative Name
    MED12/Trap230 (MED12 Products)
    Synonyms
    ARC240 antibody, CAGH45 antibody, FGS1 antibody, HOPA antibody, MED12S antibody, OHDOX antibody, OKS antibody, OPA1 antibody, TNRC11 antibody, TRAP230 antibody, 230kDa antibody, Mopa antibody, OPA-1 antibody, Tnrc11 antibody, Trap230 antibody, mediator complex subunit 12 antibody, MED12 antibody, Med12 antibody, med12 antibody
    Background

    Synonyms: Mediator of RNA polymerase II transcription subunit 12, MED12, Activator-recruited cofactor 240 kDa component, ARC240, CAG repeat protein 45 Mediator complex subunit 12, OPA-containing protein, Thyroid hormone receptor-associated protein complex 230 kDa component, Trap230, Trinucleotide repeat-containing gene 11 protein, MED12, ARC240, CAGH45, HOPA, KIAA0192, TNRC11, TRAP230

    Background: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway.

    Gene ID
    9968
    UniProt
    Q93074
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Tube Formation
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