PRAX antibody (C-Term)

Catalog No. ABIN5671378

Product Details anti-PRAX Antibody

Target: PRAX (LOC101460642) (Golgin Subfamily A Member 6-Like Protein 6 (LOC101460642))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Application: Western Blotting (WB)

Sequence: SRGQEGDAAP KSPVREKSPK FRFPRVSLSP KARSGSGDQE EGGLRVRLPS

Characteristics: This is a rabbit polyclonal antibody against PRAX. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PRAX

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PRAX

Target: PRAX (LOC101460642) (Golgin Subfamily A Member 6-Like Protein 6 (LOC101460642))

Alternative Name: PRAX (LOC101460642 Products)

Background: This gene encodes a protein involved in peripheral nerve myelin upkeep. The encoded protein contains 2 PDZ domains which were named after PSD95 (post synaptic density protein), DlgA (Drosophila disc large tumor suppressor), and ZO1 (a mammalian tight junction protein). Two alternatively spliced transcript variants have been described for this gene which encode different protein isoforms and which are targeted differently in the Schwann cell. Mutations in this gene cause Charcot-Marie-Tooth neuoropathy, type 4F and Dejerine-Sottas neuropathy.

Alias Symbols: PRX, KIAA1620,

Protein Size: 1322

Gene ID: 57716