MP2K7 antibody (C-Term)
LOC108911176
Reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish (Danio rerio)
WB
Host: Rabbit
Polyclonal
unconjugated
1 image
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- Target See all MP2K7 (LOC108911176) products
- MP2K7 (LOC108911176) (Dual Specificity Mitogen-Activated Protein Kinase Kinase 7-Like (LOC108911176))
- Binding Specificity
- C-Term
- Reactivity
- Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish (Danio rerio)
- Host
- Rabbit
- Clonality
- Polyclonal
- Application
- Western Blotting (WB)
- Sequence
- KDCLTKDHRK RPKYNKLLEH SFIKRYETLE VDVASWFKDV MAKTESPRTS
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 93%
- Characteristics
- This is a rabbit polyclonal antibody against MP2K7. It was validated on Western Blot.
- Purification
- Affinity purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human MP2K7
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- MP2K7 (LOC108911176) (Dual Specificity Mitogen-Activated Protein Kinase Kinase 7-Like (LOC108911176))
- Alternative Name
- MP2K7 (LOC108911176 Products)
- Background
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The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants.
Alias Symbols: MAP2K7, JNKK2, MEK7, MKK7, PRKMK7, SKK4,
Protein Interaction Partner: MAPK8, MAP3K3, MAP3K2, UBC, FBXO6, MAP3K11, MAPK8IP1, LPXN, VRK2, RPL30, MAPK9, HSP90AA1, ATF4, JUN, WDR6, BCL10, MAP2K4, MAPK1, LRRK2, MAP3K4, MAP3K1, MYC, ELAVL1, ALK, DUSP22, DUSP19, MAPK8IP3, CNKSR1, ZAK, TRIB1, MAPK8IP2, GADD45B, CFLAR, MAP2K7, MAP3K
Protein Size: 462 - Gene ID
- 5609
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