PIKFYVE antibody (AA 342-451)

Catalog No. ABIN566937

Product Details anti-PIKFYVE Antibody

Target: PIKFYVE (phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE))

Binding Specificity: AA 342-451

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PIKFYVE antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi)

Purpose: Mouse monoclonal antibody raised against a partial recombinant PIP5K3.

Sequence: LQSTEFSETP SPDSDSVNSV EGHSEPSWFK DIKFDDSDTE QIAEEGDDNL ANSASPSKRT SVSSFQSTVD SDSAASISLN VELDNVNFHI KKPSKYPHVP PHPADQKGRR

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: PIP5K3 (NP_689884, 342 a.a. ~ 451 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 6C7

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-PIKFYVE antibody (ABIN566937)

Takasuga, Horie, Sasaki, Sun-Wada, Kawamura, Iizuka, Mizuno, Eguchi, Kofuji, Kimura, Yamazaki, Horie, Odanaga, Sato, Chida, Kontani, Harada, Katada, Suzuki, Wada, Ohnishi, Sasaki: "Critical roles of type III phosphatidylinositol phosphate kinase in murine embryonic visceral endoderm and adult intestine." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 5, pp. 1726-31, (2013) (PubMed).

Tsuruta, Green, Rousset, Dolmetsch: "PIKfyve regulates CaV1.2 degradation and prevents excitotoxic cell death." in: The Journal of cell biology, Vol. 187, Issue 2, pp. 279-94, (2009) (PubMed).

Target Details for PIKFYVE

Target: PIKFYVE (phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE))

Alternative Name: PIP5K3 (PIKFYVE Products)

Synonyms: pip5k3 antibody, wu:fo93c03 antibody, PIP5K3 antibody, fab1-like antibody, CFD antibody, FAB1 antibody, PIP5K antibody, ZFYVE29 antibody, 5230400C17Rik antibody, Pip5k antibody, Pip5k3 antibody, Pipk5k3 antibody, PipkIII antibody, p235 antibody, phosphoinositide kinase, FYVE finger containing antibody, phosphoinositide kinase, FYVE-type zinc finger containing antibody, phosphoinositide kinase, FYVE type zinc finger containing antibody, pikfyve antibody, PIKFYVE antibody, Pikfyve antibody

Background: Full Gene Name: phosphatidylinositol-3-phosphate/phosphatidylinositol 5-kinase, type III
Synonyms: CFD,FAB1,KIAA0981,MGC40423,PIKFYVE,PIP5K

Gene ID: 200576

NCBI Accession: NM_152671

Pathways: Inositol Metabolic Process