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Shugoshin antibody (AA 1-292)

SGOL1 Reactivity: Human ELISA, WB, IP Host: Mouse Monoclonal 3C11 unconjugated
Catalog No. ABIN566873
  • Target See all Shugoshin (SGOL1) Antibodies
    Shugoshin (SGOL1) (Shugoshin 1 (SGOL1))
    Binding Specificity
    • 10
    • 8
    • 7
    • 6
    • 6
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-292
    Reactivity
    • 44
    • 5
    • 5
    • 1
    • 1
    Human
    Host
    • 43
    • 2
    Mouse
    Clonality
    • 44
    • 1
    Monoclonal
    Conjugate
    • 24
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Shugoshin antibody is un-conjugated
    Application
    • 30
    • 26
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunoprecipitation (IP)
    Purpose
    Mouse monoclonal antibody raised against a full length recombinant SGOL1.
    Sequence
    MAKERCLKKS FQDSLEDIKK RMKEKRNKNL AEIGKRRSFI AAPCQIITNT STLLKNYQDN NKMLVLALEN EKSKVKEAQD IILQLRKECY YLTCQLYALK GKLTSQQTVE PAQNQEICSS GMDPNSDDSS RNLFVKDLPQ IPLEETELPG QGESFQIEAT PPETQQSPHL SLKDITNVSL YPVVKIRRLS LSPKKNKASP AVALPKRRCT ASVNYKEPTL ASKLRRGDPF TDLCFLNSPI FKQKKDLRRS KKRALEVSPA KEAIFILYYV REFVSRFPDC RKCKLETHIC LR
    Cross-Reactivity
    Human, Rat
    Characteristics
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    SGOL1 (AAH17867, 1 a.a. ~ 292 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    3C11
    Isotype
    IgG2a
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Nijenhuis, Vallardi, Teixeira, Kops, Saurin: "Negative feedback at kinetochores underlies a responsive spindle checkpoint signal." in: Nature cell biology, Vol. 16, Issue 12, pp. 1257-64, (2014) (PubMed).

    Wang, Mayer, Stemmann, Nigg: "Centromere DNA decatenation depends on cohesin removal and is required for mammalian cell division." in: Journal of cell science, Vol. 123, Issue Pt 5, pp. 806-13, (2010) (PubMed).

    Shouse, Nobumori, Liu: "A B56gamma mutation in lung cancer disrupts the p53-dependent tumor-suppressor function of protein phosphatase 2A." in: Oncogene, Vol. 29, Issue 27, pp. 3933-41, (2010) (PubMed).

    Nozawa, Nagao, Masuda, Iwasaki, Hirota, Nozaki, Kimura, Obuse: "Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation." in: Nature cell biology, Vol. 12, Issue 7, pp. 719-27, (2010) (PubMed).

    Garcia-Cruz, Brieño, Roig, Grossmann, Velilla, Pujol, Cabero, Pessarrodona, Barbero, Garcia Caldés: "Dynamics of cohesin proteins REC8, STAG3, SMC1 beta and SMC3 are consistent with a role in sister chromatid cohesion during meiosis in human oocytes." in: Human reproduction (Oxford, England), Vol. 25, Issue 9, pp. 2316-27, (2010) (PubMed).

    Hayashi-Takanaka, Yamagata, Nozaki, Kimura: "Visualizing histone modifications in living cells: spatiotemporal dynamics of H3 phosphorylation during interphase." in: The Journal of cell biology, Vol. 187, Issue 6, pp. 781-90, (2009) (PubMed).

    Fu, Ding, Yuan, Aikhionbare, Yao, Cai, Jiang, Yao: "Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis." in: Cell research, Vol. 17, Issue 7, pp. 608-18, (2007) (PubMed).

    Thein, Kleylein-Sohn, Nigg, Gruneberg: "Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity." in: The Journal of cell biology, Vol. 178, Issue 3, pp. 345-54, (2007) (PubMed).

    Dai, Sullivan, Higgins: "Regulation of mitotic chromosome cohesion by Haspin and Aurora B." in: Developmental cell, Vol. 11, Issue 5, pp. 741-50, (2006) (PubMed).

  • Target
    Shugoshin (SGOL1) (Shugoshin 1 (SGOL1))
    Alternative Name
    SGOL1 (SGOL1 Products)
    Synonyms
    sgo1 antibody, NY-BR-85 antibody, SGO antibody, Sgo1 antibody, 3300001M08Rik antibody, C81037 antibody, shugoshin 1 antibody, shugoshin centromeric cohesion 1 antibody, shugoshin 1 L homeolog antibody, Sgo1 antibody, sgo1 antibody, sgo1.L antibody, SGO1 antibody
    Background
    Full Gene Name: shugoshin-like 1 (S. pombe)
    Synonyms: NY-BR-85,SGO,Sgo1
    Gene ID
    151648
    Pathways
    Maintenance of Protein Location
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