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Recombinant ITGA4 (Natalizumab Biosimilar) antibody

Reactivity: Human FACS, BR Host: Rabbit Chimeric unconjugated Recombinant Antibody
Catalog No. ABIN5668197
  • Target See all ITGA4 (Natalizumab Biosimilar) products
    ITGA4 (Natalizumab Biosimilar)
    Antibody Type
    Recombinant Antibody
    Reactivity
    Human
    Host
    • 1
    • 1
    • 1
    • 1
    Rabbit
    Clonality
    • 3
    • 1
    Chimeric
    Conjugate
    • 4
    This ITGA4 (Natalizumab Biosimilar) antibody is un-conjugated
    Application
    Flow Cytometry (FACS), Blocking Reagent (BR)
    Specificity
    This antibody binds to the alpha 4 binds subunit of α4β1 (also known as very late antigen 4 [VLA-4] or CD49d-CD29) and α4β7 integrin
    Characteristics

    OriginalSpeciesName: Human

    OriginalFormat: IgG4

    Purification
    Purified antibody.
    Purity
    > 98 % as determined by SDS-PAGE
    Endotoxin Level
    Endotoxin is < 1.0 EU/mg as determined by the LAL method
    Immunogen
    The RAMOS cell line, a non-EBV releasing cell line, injected into mice.
    Isotype
    IgG kappa
  • Application Notes
    This antibody binds to human integrin alpha 4 and has been used to treat Multiple Sclerosis and Crohn's Disease.
    Comment

    NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar. This chimeric rabbit antibody was made using the variable domain sequences of the original human IgG4 format, for improved compatibility with existing reagents, assays and techniques.

    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % Proclin 300.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Target
    ITGA4 (Natalizumab Biosimilar)
    Abstract
    ITGA4 (Natalizumab Biosimilar) Products
    Synonyms
    CD49D antibody, IA4 antibody, integrin subunit alpha 4 antibody, ITGA4 antibody
    Background
    CD49D, alpha 4 subunit of VLA-4 receptor, ITGA4, Integrin alpha-IV
    UniProt
    P13612
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