Recombinant MS4A1 (Rituximab Biosimilar) antibody
Reactivity: Human, Cynomolgus, Rhesus Monkey
FACS
Host: Rabbit
Chimeric
10F381
unconjugated
Recombinant Antibody
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- Target See all MS4A1 (Rituximab Biosimilar) products
- MS4A1 (Rituximab Biosimilar)
- Antibody Type
- Recombinant Antibody
- Reactivity
- Human, Cynomolgus, Rhesus Monkey
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Host
- Rabbit
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Clonality
- Chimeric
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Conjugate
- This MS4A1 (Rituximab Biosimilar) antibody is un-conjugated
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Application
- Flow Cytometry (FACS)
- Purpose
- Anti-CD20 [10F381 (rituximab)], Rabbit IgG, kappa
- Specificity
- CD20 (Human B-lymphocyte-restricted differentiation antigen, Bp35), is a hydrophobic transmembrane protein with a molecular weight of approximately 35 kDa located on pre-B and mature B lymphocytes, and most B-cell non-Hodgkin's lymphomas, but is not found on stem cells, pro-B cells, normal plasma cells or other normal tissues .
- Cross-Reactivity
- Cynomolgus, Rhesus Monkey
- Characteristics
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Original Species of Ab: Human
Original Format of Ab: IgG1
- Purification
- Protein A affinity purified
- Purity
- > 98 % as determined by SDS-PAGE
- Endotoxin Level
- Endotoxin is < 1.0 EU/mg as determined by the LAL method
- Immunogen
- Human lymphoblastoid cell line SB.
- Clone
- 10F381
- Isotype
- IgG kappa
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % Proclin 300.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Target
- MS4A1 (Rituximab Biosimilar)
- Abstract
- MS4A1 (Rituximab Biosimilar) Products
- Target Type
- Biosimilar
- Background
- Leu16, B-lymphocyte antigen CD20, B-lymphocyte surface antigen B1, Bp35 Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1, CD20
- UniProt
- P11836
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