Recombinant VEGF antibody

Catalog No. ABIN5668149

Product Details anti-VEGF Antibody

Target: VEGF (Vascular Endothelial Growth Factor (VEGF))

Antibody Type: Recombinant Antibody

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This VEGF antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS), Blocking Reagent (BR)

Purpose: Anti-VEGF [A.4.6.1], Mouse IgG1, kappa

Specificity: Binds native and reduced human VEGF (isoform 165), with a Kd of 0.8 nm determined for the original clone.

Cross-Reactivity: Rat

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogen: Recombinant human VEGF.

Clone: A-4-6-1

Isotype: IgG1 kappa

Application Details

Application Notes: This is the parental antibody clone to the humanized, therapeutic antibody Bevacizumab (marketed as Avastin) binding to VEGF. VEGF is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. It induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for VEGF

Target: VEGF (Vascular Endothelial Growth Factor (VEGF))

Alternative Name: VEGF (VEGF Products)

Background: VEGF-A, Vascular Endothelial Growth Factor, VEGFA, Vascular Permeability Factor, VPF

UniProt: P15692