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Recombinant ITGAL (Efalizumab Biosimilar) antibody

Reactivity: Human BR, FACS Host: Rabbit Monoclonal hu1124 unconjugated Recombinant Antibody
Catalog No. ABIN5668045
  • Target See all ITGAL (Efalizumab Biosimilar) products
    ITGAL (Efalizumab Biosimilar)
    Antibody Type
    Recombinant Antibody
    Reactivity
    Human
    Host
    • 1
    • 1
    Rabbit
    Clonality
    • 2
    Monoclonal
    Conjugate
    • 2
    This ITGAL (Efalizumab Biosimilar) antibody is un-conjugated
    Application
    Blocking Reagent (BR), Flow Cytometry (FACS)
    Specificity
    Binds to human LFA-1.
    Characteristics

    OriginalSpeciesName: Human

    OriginalFormat: IgG1

    Purification
    Purified antibody.
    Purity
    > 98 % as determined by SDS-PAGE
    Endotoxin Level
    Endotoxin is < 1.0 EU/mg as determined by the LAL method
    Immunogen
    Efalizumab binds to CD11a, a subunit of leukocyte function antigen-1 (LFA-1), which is expressed on all leukocytes.
    Clone
    Hu1124
    Isotype
    IgG kappa
  • Application Notes
    Efalizumab binds to the LFA-1 alpha I domain blocking the ICAM-1 binding site via steric hindrance.
    Comment

    This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % Proclin 300.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Target
    ITGAL (Efalizumab Biosimilar)
    Abstract
    ITGAL (Efalizumab Biosimilar) Products
    Synonyms
    CD11A antibody, LFA-1 antibody, LFA1A antibody, integrin subunit alpha L antibody, ITGAL antibody
    Target Type
    Biosimilar
    Background
    LFA-1, integrin alpha L
    UniProt
    P20701
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