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POT1 antibody (AA 497-634)

POT1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5663924
  • Target See all POT1 Antibodies
    POT1 (Protection of Telomeres 1 (POT1))
    Binding Specificity
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 497-634
    Reactivity
    • 22
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 21
    • 1
    Rabbit
    Clonality
    • 22
    Polyclonal
    Conjugate
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This POT1 antibody is un-conjugated
    Application
    • 11
    • 9
    • 2
    • 2
    Western Blotting (WB)
    Sequence
    TIHHYGCKQC SSLRSIQNLN SLVDKTSWIP SSVAEALGIV PLQYVFVMTF TLDDGTGVLE AYLMDSDKFF QIPASEVLMD DDLQKSVDMI MDMFCPPGIK IDAYPWLECF IKSYNVTNGT DNQICYQIFD TTVAEDVI
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 497-634 of human POT1 (NP_056265.2).
    Isotype
    IgG
    Top Product
    Discover our top product POT1 Primary Antibody
  • Application Notes
    WB,1:200 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid freeze / thaw cycles
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    POT1 (Protection of Telomeres 1 (POT1))
    Alternative Name
    POT1 (POT1 Products)
    Synonyms
    HPOT1 antibody, POT1 antibody, DKFZp469P1825 antibody, pot1 antibody, 1500031H18Rik antibody, AI851169 antibody, Pot1 antibody, Pot1a antibody, protection of telomeres 1 antibody, protection of telomeres 1 L homeolog antibody, protection of telomeres 1A antibody, POT1 antibody, pot1.L antibody, Pot1a antibody, Pot1 antibody
    Background
    This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.,POT1,CMM10,GLM9,HPOT1,Epigenetics & Nuclear Signaling,Cancer,Tumor biomarkers,Cell Biology & Developmental Biology,Cell Cycle,G2/M DNA Damage Checkpoint,POT1
    Molecular Weight
    60 kDa/71 kDa
    Gene ID
    25913
    UniProt
    Q9NUX5
    Pathways
    Cell Division Cycle, Telomere Maintenance
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