GRB10 antibody (AA 1-100)

Catalog No. ABIN5663731

Product Details anti-GRB10 Antibody

Target: GRB10 (Growth Factor Receptor-Bound Protein 10 (GRB10))

Binding Specificity: AA 1-100

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRB10 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MALAGCPDSF LHHPYYQDKV EQTPRSQQDP AGPGLPAQSD RLANHQEDDV DLEALVNDMN ASLESLYSAC SMQSDTVPLL QNGQHARSQP RASGPPRSIQ

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GRB10 (NP_005302.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:1000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GRB10

Target: GRB10 (Growth Factor Receptor-Bound Protein 10 (GRB10))

Alternative Name: GRB10 (GRB10 Products)

Synonyms: grb10 antibody, zgc:91987 antibody, GRB10 antibody, grb-10 antibody, grb-ir antibody, irbp antibody, meg1 antibody, rss antibody, LOC100224775 antibody, 5730571D09Rik antibody, AI325020 antibody, Meg1 antibody, mKIAA0207 antibody, RGD1566234 antibody, GRB-IR antibody, Grb-10 antibody, IRBP antibody, MEG1 antibody, RSS antibody, growth factor receptor bound protein 10 antibody, growth factor receptor-bound protein 10a antibody, growth factor receptor bound protein 10 L homeolog antibody, growth factor receptor-bound protein 10 antibody, GRB10 antibody, grb10a antibody, grb10 antibody, grb10.L antibody, LOC100434903 antibody, Grb10 antibody

Background: The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified.,GRB10,GRB-IR,Grb-10,IRBP,MEG1,RSS,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,GRB10

Molecular Weight: 60 kDa/62 kDa/66 kDa/67 kDa

Gene ID: 2887

UniProt: Q13322

Pathways: Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2