STK33 antibody (AA 1-514)

Catalog No. ABIN566312

Product Details anti-STK33 Antibody

Target: STK33 (serine/threonine Kinase 33 (STK33))

Binding Specificity: AA 1-514

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This STK33 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Purpose: Mouse monoclonal antibody raised against a full-length recombinant STK33.

Sequence: MADSGLDKKS TKCPDCSSAS QKDVLCVCSS KTRVPPVLVV EMSQTSSIGS AESLISLERK KEKNINRDIT SRKDLPSRTS NVERKASQQQ WGRGNFTEGK VPHIRIENGA AIEEIYTFGR ILGKGSFGIV IEATDKETET KWAIKKVNKE KAGSSAVKLL EREVNILKSV KHEHIIHLEQ VFETPKKMYL VMELCEDGEL KEILDRKGHF SENETRWIIQ SLASAIAYLH NNDIVHRDLK LENIMVKSSL IDDNNEINLN IKVTDFGLAV KKQSRSEAML QATCGTPIYM APEVISAHDY SQQCDIWSIG VVMYMLLRGE PPFLASSEGK LFELIRKGEL HFENAVWNSI SDCAKSVLKQ LMKVDPAHRI TAKELLDNQW LTGNKLSSVR PTNVLEMMKE WKNNPESVEE NTTEEKNKPS TEEKLKSYQP WGNVPETNYT SDEEEEKQST TYEKQFPATS KDNFDMCSSS FTSSKLLPAE IKGEMEKTPV TPSQGTATKY PAKSGALSRT KKKL

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: STK33 (AAH31231, 1 a.a. ~ 514 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 4F7

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-STK33 antibody (ABIN566312)

Azoitei, Hoffmann, Ellegast, Ball, Obermayer, Gößele, Koch, Faber, Genze, Schrader, Kestler, Döhner, Chiosis, Glimm, Fröhling, Scholl: "Targeting of KRAS mutant tumors by HSP90 inhibitors involves degradation of STK33." in: The Journal of experimental medicine, Vol. 209, Issue 4, pp. 697-711, (2012) (PubMed).

Scholl, Fröhling, Dunn, Schinzel, Barbie, Kim, Silver, Tamayo, Wadlow, Ramaswamy, Döhner, Bullinger, Sandy, Boehm, Root, Jacks, Hahn, Gilliland: "Synthetic lethal interaction between oncogenic KRAS dependency and STK33 suppression in human cancer cells." in: Cell, Vol. 137, Issue 5, pp. 821-34, (2009) (PubMed).

Target Details for STK33

Target: STK33 (serine/threonine Kinase 33 (STK33))

Alternative Name: STK33 (STK33 Products)

Synonyms: 4921505G21Rik antibody, AW061264 antibody, serine/threonine kinase 33 antibody, STK33 antibody, Stk33 antibody

Background: Full Gene Name: serine/threonine kinase 33
Synonyms:

Gene ID: 65975