ACD antibody (AA 1-544)

Catalog No. ABIN566298

Product Details anti-ACD Antibody

Target: ACD (Adrenocortical Dysplasia Homolog (ACD))

Binding Specificity: AA 1-544

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ACD antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Mouse monoclonal antibody raised against a full length recombinant ACD.

Sequence: MPGRCQSDAA MRVNGPASRA PAGWTSGSLH TGPRAGRPRA QARGVRGRGL LLRPRPAKEL PLPRKGGAWA PAGNPGPLHP LGVAVGMAGS GRLVLRPWIR ELILGSETPS SPRAGQLLEV LQDAEAAVAG PSHAPDTSDV GATLLVSDGT HSVRCLVTRE ALDTSDWEEK EFGFRGTEGR LLLLQDCGVH VQVAEGGAPA EFYLQVDRFS LLPTEQPRLR VPGCNQDLDV QKKLYDCLEE HLSESTSSNA GLSLSQLLDE MREDQEHQGA LVCLAESCLT LEGPCTAPPV THWAASRCKA TGEAVYTVPS SMLCISENDQ LILSSLGPCQ RTQGPELPPP DPALQDLSLT LIASPPSSPS SSGTPALPGH MSSEESGTSI SLLPALSLAA PDPGQRSSSQ PSPAICSAPA TLTPRSPHAS RTPSSPLQSC TPSLSPRSHV PSPHQALVTR PQKPSLEFKE FVGLPCKNRP PFPRTGATRG AQEPCSVWEP PKRHRDGSAF QYEYEPPCTS LCARVQAARL PPQLMAWALH FLMDAQPGSE PTPM

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: ACD (AAH16904, 1 a.a. ~ 544 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 1D8-1B6

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-ACD antibody (ABIN566298)

Frank, Tran, Qu, Stohr, Segal, Xu: "The Shelterin TIN2 Subunit Mediates Recruitment of Telomerase to Telomeres." in: PLoS genetics, Vol. 11, Issue 7, pp. e1005410, (2015) (PubMed).

Abreu, Aritonovska, Reichenbach, Cristofari, Culp, Terns, Lingner, Terns: "TIN2-tethered TPP1 recruits human telomerase to telomeres in vivo." in: Molecular and cellular biology, Vol. 30, Issue 12, pp. 2971-82, (2010) (PubMed).

Target Details for ACD

Target: ACD (Adrenocortical Dysplasia Homolog (ACD))

Alternative Name: ACD (ACD Products)

Synonyms: PIP1 antibody, PTOP antibody, TINT1 antibody, TPP1 antibody, ACD antibody, ACD, shelterin complex subunit and telomerase recruitment factor antibody, adrenocortical dysplasia antibody, ACD antibody, Acd antibody

Background: Full Gene Name: adrenocortical dysplasia homolog (mouse)
Synonyms: PIP1,PTOP,TINT1,TPP1

Gene ID: 65057

Pathways: Telomere Maintenance