PLEKHG5 antibody (AA 896-995)

Catalog No. ABIN566110

Product Details anti-PLEKHG5 Antibody

Target: PLEKHG5 (Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 5 (PLEKHG5))

Binding Specificity: AA 896-995

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PLEKHG5 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Mouse monoclonal antibody raised against a partial recombinant PLEKHG5.

Sequence: SAPSRSLSEL CLAVPAPGIR TQGSPQEAGP SWDCRGAPSP GSGPGLVGCL AGEPAGSHRK RCGDLPSGAS PRVQPEPPPG VSAQHRKLTL AQLYRIRTTL

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: PLEKHG5 (NP_065682, 896 a.a. ~ 995 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 5A9

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-PLEKHG5 antibody (ABIN566110)

Ngok, Geyer, Kourtidis, Storz, Anastasiadis: "Phosphorylation-mediated 14-3-3 protein binding regulates the function of the rho-specific guanine nucleotide exchange factor (RhoGEF) Syx." in: The Journal of biological chemistry, Vol. 288, Issue 9, pp. 6640-50, (2013) (PubMed).

Ngok, Geyer, Liu, Kourtidis, Agrawal, Wu, Seerapu, Lewis-Tuffin, Moodie, Huveldt, Marx, Baraban, Storz, Horowitz, Anastasiadis: "VEGF and Angiopoietin-1 exert opposing effects on cell junctions by regulating the Rho GEF Syx." in: The Journal of cell biology, Vol. 199, Issue 7, pp. 1103-15, (2012) (PubMed).

Target Details for PLEKHG5

Target: PLEKHG5 (Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 5 (PLEKHG5))

Alternative Name: PLEKHG5 (PLEKHG5 Products)

Synonyms: PLEKHG5 antibody, plekhg5 antibody, si:ch211-15p9.7 antibody, syx antibody, syx-a antibody, DSMA4 antibody, GEF720 antibody, Syx antibody, Tech antibody, BC023181 antibody, mKIAA0720 antibody, pleckstrin homology and RhoGEF domain containing G5 antibody, pleckstrin homology domain containing, family G (with RhoGef domain) member 5a antibody, pleckstrin homology domain containing, family G (with RhoGef domain) member 5 antibody, PLEKHG5 antibody, plekhg5a antibody, plekhg5 antibody, Plekhg5 antibody

Background: Full Gene Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 5
Synonyms: DSMA4,GEF720,KIAA0720,RP4-650H14.3

Gene ID: 57449

NCBI Accession: NM_020631

Pathways: Neurotrophin Signaling Pathway