NDRG2 antibody (AA 1-96)

Catalog No. ABIN566107

Product Details anti-NDRG2 Antibody

Target: NDRG2 (NDRG Family Member 2 (NDRG2))

Binding Specificity: AA 1-96

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NDRG2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Mouse monoclonal antibody raised against a partial recombinant NDRG2.

Sequence: MAELQEVQIT EEKPLLPGQT PEAAKTHSVE TPYGSVTFTV YGTPKPKRPA ILTYHDVGLN YKSCFQPLFQ FEDMQEIIQN FVRVHVDAPG MEEGAP

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: NDRG2 (NP_057334, 1 a.a. ~ 96 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 6A5

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-NDRG2 antibody (ABIN566107)

Shen, Qu, Ma, Zheng, Chu, Liu, Li, Wang, Xu, Liu, Yao, Zhang: "Tumor suppressor NDRG2 tips the balance of oncogenic TGF-? via EMT inhibition in colorectal cancer." in: Oncogenesis, Vol. 3, pp. e86, (2014) (PubMed).

Ma, Liu, Guo, Li, Cao, Du, Lei, Hou, Xiong, Yao, Li, Li: "N-myc downstream-regulated gene 2 expression is associated with glucose transport and correlated with prognosis in breast carcinoma." in: Breast cancer research : BCR, Vol. 16, Issue 2, pp. R27, (2014) (PubMed).

Li, Xu, Cai, Gao, Shen, Zhang, Hou, Zhong, Wang, Xiong: "NDRG2 is a novel p53-associated regulator of apoptosis in C6-originated astrocytes exposed to oxygen-glucose deprivation." in: PLoS ONE, Vol. 8, Issue 2, pp. e57130, (2013) (PubMed).

Sun, Tong, Ma, Li, Li, Li, Zhou, Xiong, Cao, Yao, Wang, Shen: "NDRG2: a newly identified mediator of insulin cardioprotection against myocardial ischemia-reperfusion injury." in: Basic research in cardiology, Vol. 108, Issue 3, pp. 341, (2013) (PubMed).

Langhi, Pedraz-Cuesta, Donate, Marrero, Haro, Rodríguez: "Regulation of N-Myc downstream regulated gene 2 by bile acids." in: Biochemical and biophysical research communications, Vol. 434, Issue 1, pp. 102-9, (2013) (PubMed).

Li, Qin, Shi, Miao, Wang, Liu, Yao, Deng: "Regulation of histone acetylation by NDRG2 in glioma cells." in: Journal of neuro-oncology, Vol. 106, Issue 3, pp. 485-92, (2012) (PubMed).

Song, Zhang, Liu, Yao, Hao, Liao, Zhang, Li: "NDRG2 down-regulation and CD24 up-regulation promote tumor aggravation and poor survival in patients with gallbladder carcinoma." in: Medical oncology (Northwood, London, England), Vol. 29, Issue 3, pp. 1879-85, (2012) (PubMed).

Li, Hu, He, Li, Zhu, Hou, Zhang, Li, Zhang, Wang, Liu, Yao, Zhang: "Up-regulation of NDRG2 through nuclear factor-kappa B is required for Leydig cell apoptosis in both human and murine infertile testes." in: Biochimica et biophysica acta, Vol. 1822, Issue 2, pp. 301-13, (2012) (PubMed).

Liu, Niu, Liu, Hou, Zhang, Yao: "Microarray profiling of HepG2 cells ectopically expressing NDRG2." in: Gene, Vol. 503, Issue 1, pp. 48-55, (2012) (PubMed).

Oh, Kim, Kim, Chang, Sohn, Kim, Jung, Lee, Kim, Kim: "NDRG2 correlated with favorable recurrence-free survival inhibits metastasis of mouse breast cancer cells via attenuation of active TGF-? production." in: Carcinogenesis, Vol. 33, Issue 10, pp. 1882-8, (2012) (PubMed).

Sun, Shen, Sun, Tong, Sun, Han, Yang, Zhang, Cao, Yao, Wang: "Variation of NDRG2 and c-Myc expression in rat heart during the acute stage of ischemia/reperfusion injury." in: Histochemistry and cell biology, Vol. 135, Issue 1, pp. 27-35, (2011) (PubMed).

Li, Shen, Cai, Wang, Hou, Wang, Zeng, Zhao, Yao, Xiong: "Spatial-temporal expression of NDRG2 in rat brain after focal cerebral ischemia and reperfusion." in: Brain research, Vol. 1382, pp. 252-8, (2011) (PubMed).

Zheng, Li, Yang, Liu, Shi, Zhang, Shi, Ren, Ma, Guo, Tao, Xue, Jiang, Yao, Liu: "NDRG2 inhibits hepatocellular carcinoma adhesion, migration and invasion by regulating CD24 expression." in: BMC cancer, Vol. 11, pp. 251:1-9, (2011) (PubMed).

Yang, Zheng, Wu, Shi, Zhang, Wang, Xia, Wang, Liu, Yao, Li, Dou: "NDRG2 ameliorates hepatic fibrosis by inhibiting the TGF-?1/Smad pathway and altering the MMP2/TIMP2 ratio in rats." in: PLoS ONE, Vol. 6, Issue 11, pp. e27710, (2011) (PubMed).

Shen, Liu, Hou, Yang, Wu, Zhang, Li, Che, Lu, Zhang, Liu, Yao: "NDRG2 is highly expressed in pancreatic beta cells and involved in protection against lipotoxicity." in: Cellular and molecular life sciences : CMLS, Vol. 67, Issue 8, pp. 1371-81, (2010) (PubMed).

Shen, Zhao, Wang, Ji, Liu, Liu, Che, Lin, Li, Zhang, Yao: "Immunohistochemical detection of Ndrg2 in the mouse nervous system." in: Neuroreport, Vol. 19, Issue 9, pp. 927-31, (2008) (PubMed).

Target Details for NDRG2

Target: NDRG2 (NDRG Family Member 2 (NDRG2))

Alternative Name: NDRG2 (NDRG2 Products)

Synonyms: NDRG2 antibody, AI182517 antibody, AU040374 antibody, Ndr2 antibody, SYLD antibody, im:6909381 antibody, si:dkey-88n24.1 antibody, zgc:101847 antibody, NDRG family member 2 antibody, N-myc downstream regulated gene 2 antibody, NDRG family member 2 S homeolog antibody, ndrg2 antibody, NDRG2 antibody, Ndrg2 antibody, ndrg2.S antibody

Background: Full Gene Name: NDRG family member 2
Synonyms: DKFZp781G1938,FLJ25522,KIAA1248,SYLD

Gene ID: 57447

NCBI Accession: NM_016250