SALL4 antibody (AA 954-1053)

Catalog No. ABIN566099

Product Details anti-SALL4 Antibody

Target: SALL4 (Sal-Like 4 (SALL4))

Binding Specificity: AA 954-1053

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SALL4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Mouse monoclonal antibody raised against a partial recombinant SALL4.

Sequence: PKEILAPSVN VDPVVWNQYT SMLNGGLAVK TNEISVIQSG GVPTLPVSLG ATSVVNNATV SKMDGSQSGI SADVEKPSAT DGVPKHQFPH FLEENKIAVS

Cross-Reactivity: Human, Mouse

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: SALL4 (NP_065169, 954 a.a. ~ 1053 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 6E3

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-SALL4 antibody (ABIN566099)

Matsumoto, Ueyama, Matsumoto, Akazawa, Komori, Takeda, Murakami, Asaoka, Hojo, Tomita, Nagahara, Kajiyama, Yao, Watanabe: "Clinicopathological features of alpha-fetoprotein producing early gastric cancer with enteroblastic differentiation." in: World journal of gastroenterology, Vol. 22, Issue 36, pp. 8203-10, (2016) (PubMed).

Yoshida, Asano, Kawai, Kawamoto, Nakazawa, Kishimoto, Kushima: "Differential SALL4 immunoexpression in malignant rhabdoid tumours and epithelioid sarcomas." in: Histopathology, Vol. 66, Issue 2, pp. 252-61, (2015) (PubMed).

Kohashi, Yamada, Hotokebuchi, Yamamoto, Taguchi, Iwamoto, Oda: "ERG and SALL4 expressions in SMARCB1/INI1-deficient tumors: a useful tool for distinguishing epithelioid sarcoma from malignant rhabdoid tumor." in: Human pathology, Vol. 46, Issue 2, pp. 225-30, (2015) (PubMed).

Shibahara, Ando, Hayashi, Sakamoto, Hesegawa, Kokudo, Fukayama: "Clinicopathologic characteristics of SALL4-immunopositive hepatocellular carcinoma." in: SpringerPlus, Vol. 3, pp. 721, (2015) (PubMed).

Chapman, Medrano, Chaudhary, Hamra: "NRG1 and KITL Signal Downstream of Retinoic Acid in the Germline to Support Soma-Free Syncytial Growth of Differentiating Spermatogonia." in: Cell death discovery, Vol. 1, (2015) (PubMed).

Osada, Aishima, Hirahashi, Takizawa, Takahashi, Nakamura, Tanaka, Maehara, Takayanagi, Oda: "Combination of hepatocellular markers is useful for prognostication in gastric hepatoid adenocarcinoma." in: Human pathology, Vol. 45, Issue 6, pp. 1243-50, (2014) (PubMed).

Iwamoto, Ishida, Yoshida, Kagotani, Iwai, Okabe: "Mediastinal seminoma: a case report with special emphasis on SALL4 as a new immunocytochemical marker." in: Diagnostic cytopathology, Vol. 41, Issue 9, pp. 821-4, (2013) (PubMed).

Ota, Iihara, Ryu, Morikawa, Fukayama: "Metastatic seminomas in lymph nodes: CD10 immunoreactivity can be a pitfall of differential diagnosis." in: International journal of clinical and experimental pathology, Vol. 6, Issue 3, pp. 498-502, (2013) (PubMed).

Zeng, Yamashita, Kondo, Nio, Hayashi, Hara, Nomura, Yoshida, Hayashi, Oishi, Ikeda, Honda, Kaneko: "The transcription factor SALL4 regulates stemness of EpCAM-positive hepatocellular carcinoma." in: Journal of hepatology, Vol. 60, Issue 1, pp. 127-34, (2013) (PubMed).

Fujimoto, Sumiyoshi, Yoshizawa, Sonobe, Kobayashi, Moriyoshi, Kido, Tanaka, Koyanagi, Date, Haga: "SALL4 immunohistochemistry in non-small-cell lung carcinomas." in: Histopathology, Vol. 64, Issue 2, pp. 309-11, (2013) (PubMed).

Meguro, Yasuda: "?-Fetoprotein-producing ovarian tumor in a postmenopausal woman with germ cell differentiation." in: Annals of diagnostic pathology, Vol. 17, Issue 1, pp. 140-4, (2012) (PubMed).

Ikeda, Sato, Yoneda, Harada, Sasaki, Kitamura, Sudo, Ooi, Nakanuma: "?-Fetoprotein-producing gastric carcinoma and combined hepatocellular and cholangiocarcinoma show similar morphology but different histogenesis with respect to SALL4 expression." in: Human pathology, Vol. 43, Issue 11, pp. 1955-63, (2012) (PubMed).

Sangoi, Karamchandani, Lane, Higgins, Rouse, Brooks, McKenney: "Specificity of brachyury in the distinction of chordoma from clear cell renal cell carcinoma and germ cell tumors: a study of 305 cases." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 24, Issue 3, pp. 425-9, (2011) (PubMed).

Deisch, Raisanen, Rakheja: "Immunoexpression of SALL4 in Wilms tumors and developing kidney." in: Pathology oncology research : POR, Vol. 17, Issue 3, pp. 639-44, (2011) (PubMed).

Clark, Polosukhina, Love, Correa, Coffin, Perlman, de Caestecker, Moses, Zent: "?-Catenin and K-RAS synergize to form primitive renal epithelial tumors with features of epithelial Wilms' tumors." in: The American journal of pathology, Vol. 179, Issue 6, pp. 3045-55, (2011) (PubMed).

Forte, Schettino, Finicelli, Cipollaro, Colacurci, Cobellis, Galderisi: "Expression pattern of stemness-related genes in human endometrial and endometriotic tissues." in: Molecular medicine (Cambridge, Mass.), Vol. 15, Issue 11-12, pp. 392-401, (2009) (PubMed).

Cauffman, De Rycke, Sermon, Liebaers, Van de Velde: "Markers that define stemness in ESC are unable to identify the totipotent cells in human preimplantation embryos." in: Human reproduction (Oxford, England), Vol. 24, Issue 1, pp. 63-70, (2008) (PubMed).

Target Details for SALL4

Target: SALL4 (Sal-Like 4 (SALL4))

Alternative Name: SALL4 (SALL4 Products)

Background: Full Gene Name: sal-like 4 (Drosophila)
Synonyms: DRRS,HSAL4,MGC133050,ZNF797,dJ1112F19.1

Gene ID: 57167

NCBI Accession: NM_020436

Pathways: Stem Cell Maintenance, Tube Formation