F11R antibody (AA 1-299)

Catalog No. ABIN565503

Product Details anti-F11R Antibody

Target: F11R (F11 Receptor (F11R))

Binding Specificity: AA 1-299

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This F11R antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Proximity Ligation Assay (PLA)

Purpose: Mouse monoclonal antibody raised against a full length recombinant F11R.

Sequence: MGTKAQVERK LLCLFILAIL LCSLALGSVT VHSSEPEVRI PENNPVKLSC AYSGFSSPRV EWKFDQGDTT RLVCYNNKIT ASYEDRVTFL PTGITFKSVT REDTGTYTCM VSEEGGNSYG EVKVKLIVLV PPSKPTVNIP SSATIGNRAV LTCSEQDGSP PSEYTWFKDG IVMPTNPKST RAFSNSSYVL NPTTGELVFD PLSASDTGEY SCEARNGYGT PMTSNAVRME AVERNVGVIV AAVLVTLILL GILVFGIWFA YSRGHFDRTK KGTSSKKVIY SQPSARSEGE FKQTSSFLV

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: F11R (AAH01533, 1 a.a. ~ 299 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 2E3-1C8

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-F11R antibody (ABIN565503)

Huang, Xu, Sun, Wang, Zhu, Song, Luo, Zhang, Xu: "Low junctional adhesion molecule A expression correlates with poor prognosis in gastric cancer." in: The Journal of surgical research, Vol. 192, Issue 2, pp. 494-502, (2014) (PubMed).

Fong, Spizzo, Mitterer, Seeber, Steurer, Gastl, Brosch, Moser: "Low expression of junctional adhesion molecule A is associated with metastasis and poor survival in pancreatic cancer." in: Annals of surgical oncology, Vol. 19, Issue 13, pp. 4330-6, (2012) (PubMed).

Gutwein, Schramme, Voss, Abdel-Bakky, Doberstein, Ludwig, Altevogt, Hansmann, Moch, Kristiansen, Pfeilschifter: "Downregulation of junctional adhesion molecule-A is involved in the progression of clear cell renal cell carcinoma." in: Biochemical and biophysical research communications, Vol. 380, Issue 2, pp. 387-91, (2009) (PubMed).

McSherry, McGee, Jirstrom, Doyle, Brennan, Landberg, Dervan, Hopkins, Gallagher: "JAM-A expression positively correlates with poor prognosis in breast cancer patients." in: International journal of cancer. Journal international du cancer, Vol. 125, Issue 6, pp. 1343-51, (2009) (PubMed).

Target Details for F11R

Target: F11R (F11 Receptor (F11R))

Alternative Name: F11R (F11R Products)

Synonyms: CD321 antibody, JAM antibody, JAM1 antibody, JAMA antibody, JCAM antibody, KAT antibody, PAM-1 antibody, 9130004G24 antibody, AA638916 antibody, ESTM33 antibody, JAM-1 antibody, JAM-A antibody, Jcam antibody, Jcam1 antibody, Ly106 antibody, Jam1 antibody, F11 receptor antibody, F11R antibody, F11r antibody

Background: Full Gene Name: F11 receptor
Synonyms: CD321,JAM,JAM-1,JAM-A,JAM1,JAMA,JCAM,KAT,PAM-1

Gene ID: 50848

Pathways: Cell-Cell Junction Organization