DEF6 antibody (AA 1-336)

Catalog No. ABIN565491

Product Details anti-DEF6 Antibody

Target: DEF6 (Differentially Expressed in FDCP 6 Homolog (DEF6))

Binding Specificity: AA 1-336

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DEF6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Purpose: Mouse monoclonal antibody raised against a full length recombinant DEF6.

Sequence: MALRKELLKS IWYAFTALDV EKSGKVSKSQ LKVLSHNLYT VLHIPHDPVA LEEHFRDDDD GPVSSQGYMP YLNKYILDKV EEGAFVKEHF DELCWTLTAK KNYRADSNGN SMLSNQDAFR LWCLFNFLSE DKYPLIMVPD EVEYLLKKVL SSMSLEVSLG ELEELLAQEA QVAQTTGGLS VWQFLELFNS GRCLRGVGRD TLSMAIHEVY QELIQDVLKQ GYLWKRGHLR RNWAERWFQL QPSCLCYFGS EECKEKRGII PLDAHCCVEV LPDRDGKRCM FCVKTATRTY EMSASDTRQR QEWTAAIQMA IRLQAEGKTS LHKDLKQKRR EQREQR

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: DEF6 (AAH17504, 1 a.a. ~ 336 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 1F2

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-DEF6 antibody (ABIN565491)

Liew, Fang, Lee, Lee, Chen, Chu: "DEF6 expression in ovarian carcinoma correlates with poor patient survival." in: Diagnostic pathology, Vol. 11, Issue 1, pp. 68, (2016) (PubMed).

Worthmann, Leitges, Teng, Sestu, Tossidou, Samson, Haller, Huber, Schiffer: "Def-6, a novel regulator of small GTPases in podocytes, acts downstream of atypical protein kinase C (aPKC) ?/?." in: The American journal of pathology, Vol. 183, Issue 6, pp. 1945-59, (2013) (PubMed).

Target Details for DEF6

Target: DEF6 (Differentially Expressed in FDCP 6 Homolog (DEF6))

Alternative Name: DEF6 (DEF6 Products)

Background: Full Gene Name: differentially expressed in FDCP 6 homolog (mouse)
Synonyms: IBP,SLAT

Gene ID: 50619