Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Buffer
In 1x PBS, pH 7.4
Handling Advice
Aliquot to avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Kienzle, Basnet, Crevenna, Beck, Habermann, Mizuno, von Blume: "Cofilin recruits F-actin to SPCA1 and promotes Ca2+-mediated secretory cargo sorting." in: The Journal of cell biology, Vol. 206, Issue 5, pp. 635-54, (2014) (PubMed).
Grice, Vetter, Faddy, Kenny, Roberts-Thomson, Monteith: "Golgi calcium pump secretory pathway calcium ATPase 1 (SPCA1) is a key regulator of insulin-like growth factor receptor (IGF1R) processing in the basal-like breast cancer cell line MDA-MB-231." in: The Journal of biological chemistry, Vol. 285, Issue 48, pp. 37458-66, (2010) (PubMed).
Target
ATP2C1
(ATPase, Ca++ Transporting, Type 2C, Member 1 (ATP2C1))