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POLI antibody (AA 616-715)

POLI Reactivity: Human WB, ELISA Host: Mouse Monoclonal 8G9 unconjugated
Catalog No. ABIN564869
  • Target See all POLI Antibodies
    POLI (Polymerase (DNA Directed) iota (POLI))
    Binding Specificity
    • 15
    • 8
    • 8
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 616-715
    Reactivity
    • 40
    • 26
    • 11
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 53
    • 2
    Mouse
    Clonality
    • 53
    • 2
    Monoclonal
    Conjugate
    • 20
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This POLI antibody is un-conjugated
    Application
    • 27
    • 26
    • 17
    • 13
    • 13
    • 6
    • 4
    • 4
    • 3
    • 3
    Western Blotting (WB), ELISA
    Purpose
    Mouse monoclonal antibody raised against a partial recombinant POLI.
    Sequence
    PQGFHFTNSN PAVSAFHSFP NLQSEQLFSR NHTTDSHKQT VATDSHEGLT ENREPDSVDE KITFPSDIDP QVFYELPEAV QKELLAEWKR AGSDFHIGHK
    Cross-Reactivity
    Human
    Characteristics
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    POLI (AAH32662, 616 a.a. ~ 715 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    8G9
    Isotype
    IgG3
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Sekimoto, Oda, Kurashima, Hanaoka, Yamashita: "Both high-fidelity replicative and low-fidelity Y-family polymerases are involved in DNA rereplication." in: Molecular and cellular biology, Vol. 35, Issue 4, pp. 699-715, (2015) (PubMed).

    Takezawa, Ishimi, Aiba, Yamada: "Rev1, Rev3, or Rev7 siRNA Abolishes Ultraviolet Light-Induced Translesion Replication in HeLa Cells: A Comprehensive Study Using Alkaline Sucrose Density Gradient Sedimentation." in: Journal of nucleic acids, Vol. 2010, pp. 750296, (2010) (PubMed).

    Wang, Woodgate, McManus, Mead, McCormick, Maher: "Evidence that in xeroderma pigmentosum variant cells, which lack DNA polymerase eta, DNA polymerase iota causes the very high frequency and unique spectrum of UV-induced mutations." in: Cancer research, Vol. 67, Issue 7, pp. 3018-26, (2007) (PubMed).

  • Target
    POLI (Polymerase (DNA Directed) iota (POLI))
    Alternative Name
    POLI (POLI Products)
    Synonyms
    poli antibody, wu:fc27h11 antibody, zgc:110185 antibody, GB12093 antibody, NV16187 antibody, RAD30B antibody, RAD3OB antibody, Rad30b antibody, DNA polymerase iota antibody, polymerase (DNA directed) iota antibody, polymerase (DNA directed), iota antibody, POLI antibody, poli antibody, LOC551219 antibody, AFUA_4G11140 antibody, LOC5568276 antibody, Pol-iota antibody, Poli antibody
    Background
    Full Gene Name: polymerase (DNA directed) iota
    Synonyms: RAD30B,RAD3OB
    Gene ID
    11201
    Pathways
    DNA Damage Repair
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