NOV antibody (AA 334-357)

Catalog No. ABIN5647955

Product Details anti-NOV Antibody

Target: NOV (Nephroblastoma Overexpressed (NOV))

Binding Specificity: AA 334-357

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NOV antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity purified

Immunogen: Amino acids 334-357 (HTNCPKNNEAFLQELELKTTRGKM) were used as the immunogen for the CCN3 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the CCN3 antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the CCN3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for NOV

Target: NOV (Nephroblastoma Overexpressed (NOV))

Alternative Name: CCN3 / NOV / IGFBP9 (NOV Products)

Synonyms: CCN3 antibody, IBP-9 antibody, IGFBP-9 antibody, IGFBP9 antibody, NOVh antibody, nov-A antibody, xnov antibody, NovH antibody, C130088N23Rik antibody, nephroblastoma overexpressed antibody, nephroblastoma overexpressed L homeolog antibody, nephroblastoma overexpressed gene antibody, NOV antibody, nov.L antibody, Nov antibody

Background: NOV (nephroblastoma overexpressed), also known as CCN3, is a matricellular protein that in humans is encoded by the NOV gene. The protein encoded by this gene is a small secreted cysteine-rich protein and a member of the CCN family of regulatory proteins. CNN family proteins associate with the extracellular matrix and play an important role in cardiovascular and skeletal development, fibrosis and cancer development.

UniProt: P48745

Pathways: Smooth Muscle Cell Migration, Growth Factor Binding