Acrosin antibody (AA 99-127)

Catalog No. ABIN5647947

Product Details anti-Acrosin Antibody

Target: Acrosin (ACR)

Binding Specificity: AA 99-127

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Acrosin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purification: Purified

Immunogen: A portion of amino acids 99-127 from the human protein was used as the immunogen for this ACR antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Western blot: 1:250-1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the ACR antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for Acrosin

Target: Acrosin (ACR)

Alternative Name: ACR / Acrosin (ACR Products)

Synonyms: ACR antibody, MGC130972 antibody, Acro antibody, Acrosin antibody, acrosin antibody, acrosin L homeolog antibody, acrosin prepropeptide antibody, ACR antibody, acr.L antibody, Acr antibody

Background: Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids.

UniProt: P10323

Pathways: cAMP Metabolic Process