IL1F6
Reactivity: Human
WB
Host: Mouse
Polyclonal
unconjugated
Application Notes
Optimal dilution of the IL-36 alpha antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,Direct ELISA (recombinant human protein): 0.1-0.5 μg/mL (BSA-free format available)
Restrictions
For Research Use only
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Storage
-20 °C
Storage Comment
After reconstitution, the IL-36 alpha antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Target
IL36A/IL1F6 (IL1F6)
(Interleukin 1 Family, Member 6 (IL1F6))
Interleukin-36 alpha also known as interleukin-1 family member 6 (IL1F6) is a protein that in humans is encoded by the IL36A gene. The protein encoded by this gene is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this gene has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients.