MLLT11
Reactivity: Human
IF (cc), IF (p)
Host: Rabbit
Polyclonal
AbBy Fluor® 594
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Buffer
In 1x PBS, pH 7.4
Handling Advice
Aliquot to avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Yamada, Clark, Iulianella: "MLLT11/AF1q is differentially expressed in maturing neurons during development." in: Gene expression patterns : GEP, Vol. 15, Issue 2, pp. 80-7, (2014) (PubMed).
Tiberio, Cavadini, Callari, Daidone, Appierto: "AF1q: a novel mediator of basal and 4-HPR-induced apoptosis in ovarian cancer cells." in: PLoS ONE, Vol. 7, Issue 6, pp. e39968, (2012) (PubMed).
Parcelier, Maharzi, Delord, Robledo-Sarmiento, Nelson, Belakhdar-Mekid, Pla, Kuranda, Parietti, Goodhardt, Legrand, Bernstein, Gluckman, Sigaux, Canque: "AF1q/MLLT11 regulates the emergence of human prothymocytes through cooperative interaction with the Notch signaling pathway." in: Blood, Vol. 118, Issue 7, pp. 1784-96, (2011) (PubMed).
Chang, Li, Hou, Wu, Lu, Di, Jin, Ou, Shen, Shao: "Identification of the functional role of AF1Q in the progression of breast cancer." in: Breast cancer research and treatment, Vol. 111, Issue 1, pp. 65-78, (2008) (PubMed).
Co, Tsang, Wong, Cheung, Tsang, Kong, Kwok: "Oncogene AF1q enhances doxorubicin-induced apoptosis through BAD-mediated mitochondrial apoptotic pathway." in: Molecular cancer therapeutics, Vol. 7, Issue 10, pp. 3160-8, (2008) (PubMed).
Target
MLLT11
(Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog), Translocated To, 11 (MLLT11))