BAG1 antibody (AA 323-345)

Catalog No. ABIN5647493

Product Details anti-BAG1 Antibody

Target: BAG1 (BCL2-Associated Athanogene (BAG1))

Binding Specificity: AA 323-345

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAG1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity (Details): Expected species reactivity: Human

Purification: Antigen affinity purified

Immunogen: Amino acids 323-345 (DTVEQNICQETERLQSTNFALAE) from the human protein were used as the immunogen for the BAG1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the BAG1 antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the BAG1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for BAG1

Target: BAG1 (BCL2-Associated Athanogene (BAG1))

Alternative Name: BAG1 (BAG1 Products)

Synonyms: BAG-1 antibody, HAP antibody, RAP46 antibody, Rap46 antibody, Bag-1 antibody, ATBAG1 antibody, BCL-2-associated athanogene 1 antibody, MSG15.15 antibody, MSG15_15 antibody, im:7148830 antibody, si:dkey-216e9.4 antibody, BCL2 associated athanogene 1 antibody, putative bcl2-associated athanogene antibody, BCL2-associated athanogene 1 antibody, Bcl2 associated athanogene 1 antibody, BAG family molecular chaperone regulator 1 antibody, BCL-2-associated athanogene 1 antibody, BAG1 antibody, Smp_005900 antibody, Bag1 antibody, bag-1 antibody, LOC781741 antibody, bag1 antibody

Background: BAG family molecular chaperone regulator 1 (BAG1) is a protein that in humans is encoded by the BAG1 gene. Human BAG1 is mapped to chromosome 9p12, a region associated with hereditary disorders that may involve developmental dysregulation of programmed cell death. The Bag1 protein is rich in glutamic acid residues. Its deduced 274-amino acid protein has a calculated molecular mass of 31 KD. Being the BCL-2-associated athanogene, Bag1 enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms.

UniProt: Q99933