The stated application concentrations are suggested starting points. Titration of the APLP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. WB: 1:1000-1:2000
Restrictions
For Research Use only
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the APLP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
APLP1
(Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))
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Background
Amyloid-like protein 1 may play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I.