MXD1 antibody
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- Target See all MXD1 Antibodies
- MXD1 (MAX Dimerization Protein 1 (MXD1))
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Reactivity
- Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MXD1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Cross-Reactivity (Details)
- Expected species reactivity: Human
- Purification
- Antigen affinity purified
- Immunogen
- A recombinant human protein corresponding to amino acids M1-L221 was used as the immunogen for the MAD antibody.
- Isotype
- IgG
- Top Product
- Discover our top product MXD1 Primary Antibody
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- Application Notes
- Optimal dilution of the MAD antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,Direct ELISA: 0.1-0.5 μg/mL
- Restrictions
- For Research Use only
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Storage
- -20 °C
- Storage Comment
- After reconstitution, the MAD antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Target
- MXD1 (MAX Dimerization Protein 1 (MXD1))
- Alternative Name
- MAD / MXD1 / Max dimerization protein 1 (MXD1 Products)
- Synonyms
- MXD1 antibody, si:dkey-202n14.4 antibody, xmad1 antibody, BHLHC58 antibody, MAD antibody, MAD1 antibody, AW122478 antibody, Mad antibody, Mad1 antibody, Mad-1 antibody, MAX dimerization protein 1 antibody, MAX dimerization protein 1 L homeolog antibody, max dimerization protein 1 antibody, MXD1 antibody, mxd1 antibody, mxd1.L antibody, Mxd1 antibody
- Background
- MAD protein is a protein that in humans is encoded by the MXD1 gene. This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
- UniProt
- Q05195
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