Dynamin 1-Like antibody (AA 1-710)

Catalog No. ABIN564347

Product Details anti-Dynamin 1-Like Antibody

Target: Dynamin 1-Like (DNM1L)

Binding Specificity: AA 1-710

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Dynamin 1-Like antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Mouse monoclonal antibody raised against a full length recombinant DNM1L.

Sequence: MEALIPVINK LQDVFNTVGA DIIQLPQIVV VGTQSSGKSS VLESLVGRDL LPRGTGIVTR RPLILQLVHV SQEDKRKTTG EENGVEAEEW GKFLHTKNKL YTDFDEIRQE IENETERISG NNKGVSPEPI HLKIFSPNVV NLTLVDLPGM TKVPVGDQPK DIELQIRELI LRFISNPNSI ILAVTAANTD MATSEALKIS REVDPDGRRT LAVITKLDLM DAGTDAMDVL MGRVIPVKLG IIGVVNRSQL DINNKKSVTD SIRDEYAFLQ KKYPSLANRN GTKYLARTLN RLLMHHIRDC LPELKTRINV LAAQYQSLLN SYGEPVDDKS ATLLQLITKF ATEYCNTIEG TAKYIETSEL CGGARICYIF HETFGRTLES VDPLGGLNTI DILTAIRNAT GPRPALFVPE VSFELLVKRQ IKRLEEPSLR CVELVHEEMQ RIIQHCSNYS TQELLRFPKL HDAIVEVVTC LLRKRLPVTN EMVHNLVAIE LAYINTKHPD FADACGLMNN NIEEQRRNRL ARELPSAVSR DKLIQDSRRE TKNVASGGGG VGDGVQEPTT GNWRGMLKTS KAEELLAEEK SKPIPIMPAS PQKGHAVNLL DVPVPVARKL SAREQRDCEV IERLIKSYFL IVRKNIQDSV PKAVMHFLVN HVKDTLQSEL VGQLYKSSLL DDLLTESEDM AQRRKEAADM LKALQGASQI IAEIRETHLW

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: DNM1L (AAH24590.1, 1 a.a. ~ 710 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 3B5

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Dynamin 1-Like antibody (ABIN564347)

Kim, McLean, Philip, Feldman: "Hyperinsulinemia induces insulin resistance in dorsal root ganglion neurons." in: Endocrinology, Vol. 152, Issue 10, pp. 3638-47, (2011) (PubMed).

Edwards, Quattrini, Lentz, Figueroa-Romero, Cerri, Backus, Hong, Feldman: "Diabetes regulates mitochondrial biogenesis and fission in mouse neurons." in: Diabetologia, Vol. 53, Issue 1, pp. 160-9, (2010) (PubMed).

Vincent, Edwards, McLean, Hong, Cerri, Lopez, Quattrini, Feldman: "Mitochondrial biogenesis and fission in axons in cell culture and animal models of diabetic neuropathy." in: Acta neuropathologica, Vol. 120, Issue 4, pp. 477-89, (2010) (PubMed).

Figueroa-Romero, Iñiguez-Lluhí, Stadler, Chang, Arnoult, Keller, Hong, Blackstone, Feldman: "SUMOylation of the mitochondrial fission protein Drp1 occurs at multiple nonconsensus sites within the B domain and is linked to its activity cycle." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 11, pp. 3917-27, (2009) (PubMed).

Target Details for Dynamin 1-Like

Target: Dynamin 1-Like (DNM1L)

Alternative Name: DNM1L (DNM1L Products)

Synonyms: DLP1 antibody, DRP1 antibody, DVLP antibody, DYMPLE antibody, EMPF antibody, HDYNIV antibody, 6330417M19Rik antibody, AI450666 antibody, Dlp1 antibody, Dnmlp1 antibody, Drp1 antibody, python antibody, Dnml1 antibody, dnm1l antibody, MGC53850 antibody, zgc:66163 antibody, DNM1L antibody, 18.m06247 antibody, CG3210 antibody, DRP antibody, Dmel\CG3210 antibody, Dnm1/Drp1 antibody, Drp antibody, Drp-1 antibody, drp-1 antibody, drp1 antibody, frat antibody, l(2)22Fc antibody, l(2)22Fd antibody, l(2)ND2 antibody, l(2)ND3 antibody, dynamin 1 like antibody, dynamin 1-like antibody, dynamin 1-like L homeolog antibody, dynamin-1-like antibody, dynamin-1-like protein antibody, dynamin-like protein antibody, Dynamin related protein 1 antibody, DNM1L antibody, Dnm1l antibody, dnm1l.L antibody, dnm1l antibody, LOC100369408 antibody, LOC411472 antibody, dyn1 antibody, cgd1_580 antibody, EHI_052740 antibody, PVX_092875 antibody, BBOV_II002980 antibody, Drp1 antibody

Background: Full Gene Name: dynamin 1-like
Synonyms: DLP1,DRP1,DVLP,DYMPLE,DYNIV-11,FLJ41912,HDYNIV,VPS1

Gene ID: 10059