FAIM3 antibody (AA 124-223)

Catalog No. ABIN563980

Product Details anti-FAIM3 Antibody

Target: FAIM3 (Fas Apoptotic Inhibitory Molecule 3 (FAIM3))

Binding Specificity: AA 124-223

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FAIM3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Mouse monoclonal antibody raised against a partial recombinant FAIM3.

Sequence: SEYEPSWEEQ PMPETPKWFH LPYLFQMPAY ASSSKFVTRV TTPAQRGKVP PVHHSSPTTQ ITHRPRVSRA SSVAGDKPRT FLPSTTASKI SALEGLLKPQ

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: FAIM3 (AAH06401, 124 a.a. ~ 223 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 1E4

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-FAIM3 antibody (ABIN563980)

Murakami, Narayanan, Su, Childs, Krzewski, Borrego, Weck, Coligan: "Toso, a functional IgM receptor, is regulated by IL-2 in T and NK cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 189, Issue 2, pp. 587-97, (2012) (PubMed).

Li, Kubagawa, McCollum, Wilson, Motohashi, Bertoli, Barton, Barnes, Davis, Kubagawa: "Enhanced levels of both the membrane-bound and soluble forms of IgM Fc receptor (Fc?R) in patients with chronic lymphocytic leukemia." in: Blood, Vol. 118, Issue 18, pp. 4902-9, (2011) (PubMed).

Proto-Siqueira, Panepucci, Careta, Lee, Clear, Morris, Owen, Rizzatti, Silva, Falcão, Zago, Gribben: "SAGE analysis demonstrates increased expression of TOSO contributing to Fas-mediated resistance in CLL." in: Blood, Vol. 112, Issue 2, pp. 394-7, (2008) (PubMed).

Target Details for FAIM3

Target: FAIM3 (Fas Apoptotic Inhibitory Molecule 3 (FAIM3))

Alternative Name: FAIM3 (FAIM3 Products)

Background: Full Gene Name: Fas apoptotic inhibitory molecule 3
Synonyms: TOSO

Gene ID: 9214