HGS antibody (AA 513-612)

Catalog No. ABIN563958

Product Details anti-HGS Antibody

Target: HGS (Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS))

Binding Specificity: AA 513-612

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HGS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), RNA Interference (RNAi)

Purpose: Mouse monoclonal antibody raised against a partial recombinant HGS.

Sequence: KLEIMRQKKQ EYLEVQRQLA IQRLQEQEKE RQMRLEQQKQ TVQMRAQMPA FPLPYAQLQA MPAAGGVLYQ PSGPASFPST FSPAGSVEGS PMHGVYMSQP

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: HGS (AAH03565, 513 a.a. ~ 612 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 6D11

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-HGS antibody (ABIN563958)

McLeod, Zhou, Li, Wang, He: "The class III kinase Vps34 promotes T lymphocyte survival through regulating IL-7R? surface expression." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 10, pp. 5051-61, (2011) (PubMed).

Target Details for HGS

Target: HGS (Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS))

Alternative Name: HGS (HGS Products)

Background: Full Gene Name: hepatocyte growth factor-regulated tyrosine kinase substrate
Synonyms: HRS,ZFYVE8

Gene ID: 9146

Pathways: EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Synaptic Vesicle Exocytosis, EGFR Downregulation