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ADAM17 antibody (AA 215-314)

Name: ADAM17 antibody (AA 215-314)
SKU: ABIN563080
Price: 651.43 USD
Availability: InStock

ADAM17 Reactivity: Human WB, ELISA, IHC (p), PLA Host: Mouse Monoclonal 1F6 unconjugated

ADAM17 monoclonal antibody (M01), clone 1F6. (ADAM17 antibody (AA 215-314))

Western Blot detection against Immunogen (36. (ADAM17 antibody (AA 215-314))

Immunoperoxidase of monoclonal antibody to ADAM17 on formalin-fixed paraffin-embedded human small Intestine. (ADAM17 antibody (AA 215-314))

ISt

Detection limit for recombinant GST tagged ADAM17 is approximately 3ng/ml as a capture antibody. (ADAM17 antibody (AA 215-314))

ELISA

Proximity Ligation Analysis of protein-protein interactions between TGFA and ADAM17. (ADAM17 antibody (AA 215-314))

PLA

5 images

(1 reference)

Catalog No. ABIN563080

Datasheet as PDF

Target See all ADAM17 Antibodies

ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
Binding Specificity
16

8

8

7

5

5

4

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 215-314
Reactivity
92

45

43

3

3

3

1
Human
Host
78

13

1

1

1
Mouse
Compatible Secondaries
Clonality
70

24
Monoclonal
Conjugate
48

7

6

5

4

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This ADAM17 antibody is un-conjugated
Application
74

44

36

15

14

11

11

10

9

4

4

4

3

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Proximity Ligation Assay (PLA)

Purpose

Mouse monoclonal antibody raised against a partial recombinant ADAM17.

Sequence

RADPDPMKNT CKLLVVADHR FYRYMGRGEE STTTNYLIEL IDRVDDIYRN TSWDNAGFKG YGIQIEQIRI LKSPQEVKPG EKHYNMAKSY PNEEKDAWDV

Cross-Reactivity

Human

Characteristics

Antibody Reactive Against Recombinant Protein.

Immunogen

ADAM17 (NP_003174, 215 a.a. ~ 314 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone

1F6

Isotype

IgG2b

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ADAM17 Reactivity: Human WB, ELISA, IHC, IHC (p), PLA Host: Mouse Monoclonal 1F6 unconjugated

anti-ADAM Metallopeptidase Domain 17 (ADAM17) (AA 215-315) antibody
ADAM17 Reactivity: Human WB, IHC (p), EIA Host: Mouse Monoclonal 1F6 unconjugated

anti-ADAM Metallopeptidase Domain 17 (ADAM17) (C-Term) antibody
ADAM17 Reactivity: Human, Rat, Mouse WB, IF, EIA Host: Rabbit Polyclonal unconjugated

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Buffer

In 1x PBS, pH 7.4

Handling Advice

Aliquot to avoid repeated freezing and thawing.

Storage

-20 °C

Storage Comment

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Kahlert, Weber, Mogler, Bergmann, Schirmacher, Kenngott, Matterne, Mollberg, Rahbari, Hinz, Koch, Aigner, Weitz: "Increased expression of ALCAM/CD166 in pancreatic cancer is an independent prognostic marker for poor survival and early tumour relapse." in: British journal of cancer, Vol. 101, Issue 3, pp. 457-64, (2009) (PubMed).
Target

ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

Alternative Name

ADAM17 (ADAM17 Products)

Background

Full Gene Name: ADAM metallopeptidase domain 17
Synonyms: CD156b,MGC71942,TACE,cSVP

Gene ID

6868

NCBI Accession

NM_003183

Pathways

Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus