RAB27A antibody (AA 122-221)
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- Target See all RAB27A Antibodies
- RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))
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Binding Specificity
- AA 122-221
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This RAB27A antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi)
- Purpose
- Mouse monoclonal antibody raised against a partial recombinant RAB27A.
- Sequence
- YCENPDIVLC GNKSDLEDQR VVKEEEAIAL AEKYGIPYFE TSAANGTNIS QAIEMLLDLI MKRMERCVDK SWIPEGVVRS NGHASTDQLS EEKEKGACGC
- Cross-Reactivity
- Human
- Characteristics
- Antibody Reactive Against Recombinant Protein.
- Immunogen
- RAB27A (NP_004571, 122 a.a. ~ 221 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Clone
- 1G7
- Isotype
- IgG1
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- In 1x PBS, pH 7.4
- Handling Advice
- Aliquot to avoid repeated freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Exosome-mediated transfer of miR-222 is sufficient to increase tumor malignancy in melanoma." in: Journal of translational medicine, Vol. 14, pp. 56, (2016) (PubMed).
: "Exosome-mediated microRNA signaling from breast cancer cells is altered by the anti-angiogenesis agent docosahexaenoic acid (DHA)." in: Molecular cancer, Vol. 14, pp. 133, (2015) (PubMed).
: "Patients with Griscelli syndrome and normal pigmentation identify RAB27A mutations that selectively disrupt MUNC13-4 binding." in: The Journal of allergy and clinical immunology, (2014) (PubMed).
: "Activated Cdc42-bound IQGAP1 determines the cellular endocytic site." in: Molecular and cellular biology, Vol. 33, Issue 24, pp. 4834-43, (2013) (PubMed).
: "Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. ..." in: Nature medicine, Vol. 18, Issue 6, pp. 883-91, (2012) (PubMed).
: "Stepwise maturation of lytic granules during differentiation and activation of human CD8+ T lymphocytes." in: PLoS ONE, Vol. 6, Issue 11, pp. e27057, (2011) (PubMed).
: "Synaptotagmin-like protein 1 interacts with the GTPase-activating protein Rap1GAP2 and regulates dense granule secretion in platelets." in: Blood, Vol. 114, Issue 7, pp. 1396-404, (2009) (PubMed).
: "The GDP-dependent Rab27a effector coronin 3 controls endocytosis of secretory membrane in insulin-secreting cell lines." in: Journal of cell science, Vol. 121, Issue Pt 18, pp. 3092-8, (2008) (PubMed).
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Exosome-mediated transfer of miR-222 is sufficient to increase tumor malignancy in melanoma." in: Journal of translational medicine, Vol. 14, pp. 56, (2016) (PubMed).
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- Target
- RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))
- Alternative Name
- RAB27A (RAB27A Products)
- Synonyms
- MGC80943 antibody, RAB27A antibody, gs2 antibody, ram antibody, rab27 antibody, MGC89827 antibody, hst18676 antibody, zgc:114135 antibody, GS2 antibody, HsT18676 antibody, RAB27 antibody, RAM antibody, 2210402C08Rik antibody, 2410003M20Rik antibody, 4933437C11Rik antibody, ash antibody, RAB27A, member RAS oncogene family L homeolog antibody, RAB27A, member RAS oncogene family antibody, RAB27A, member RAS oncogene family S homeolog antibody, rab27a.L antibody, RAB27A antibody, rab27a antibody, rab27a.S antibody, Rab27a antibody
- Background
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Full Gene Name: RAB27A, member RAS oncogene family
Synonyms: GS2,HsT18676,MGC117246,RAB27,RAM - Gene ID
- 5873
- NCBI Accession
- NM_004580
- Pathways
- Peptide Hormone Metabolism
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