LGMN antibody (AA 1-433)

Catalog No. ABIN562455

Product Details anti-LGMN Antibody

Target: LGMN (Legumain (LGMN))

Binding Specificity: AA 1-433

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LGMN antibody is un-conjugated

Application: ELISA

Purpose: Mouse monoclonal antibody raised against a partial recombinant LGMN.

Sequence: MVWKVAVFLS VALGIGAIPI DDPEDGGKHW VVIVAGSNGW YNYRHQADAC HAYQIIHRNG IPDEQIVVMM YDDIAYSEDN PTPGIVINRP NGTDVYQGVP KDYTGEDVTP QNFLAVLRGD AEAVKGIGSG KVLKSGPQDH VFIYFTDHGS TGILVFPNED LHVKDLNETI HYMYKHKMYR KMVFYIEACE SGSMMNHLPD NINVYATTAA NPRESSYACY YDEKRSTYLG DWYSVNWMED SDVEDLTKET LHKQYHLVKS HTNTSHVMQY GNKTISTMKV MQFQGMKRKA SSPVPLPPVT HLDLTPSPDV PLTIMKRKLM NTNDLEESRQ LTEEIQRHLD ARHLIEKSVR KIVSLLAASE AEVEQLLSER APLTGHSCYP EALLHFRTHC FNWHSPTYEY ALRHLYVLVN LCEKPYPLHR IKLSMDHVCL GHY

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: LGMN (AAH03061.1, 1 a.a. ~ 433 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: M1

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-LGMN antibody (ABIN562455)

Liu, Bajjuri, Liu, Sinha: "Targeting cell surface alpha(v)beta(3) integrin increases therapeutic efficacies of a legumain protease-activated auristatin prodrug." in: Molecular pharmaceutics, Vol. 9, Issue 1, pp. 168-75, (2012) (PubMed).

Target Details for LGMN

Target: LGMN (Legumain (LGMN))

Alternative Name: LGMN (LGMN Products)

Synonyms: AEP antibody, LGMN1 antibody, PRSC1 antibody, AI746452 antibody, AU022324 antibody, Prsc1 antibody, MGC64351 antibody, cb173 antibody, cb460 antibody, sb:cb173 antibody, zgc:76953 antibody, wu:fa98g05 antibody, wu:fj92g08 antibody, lgmn antibody, MGC88980 antibody, DELTA VACUOLAR PROCESSING ENZYME antibody, DELTAVPE antibody, delta vacuolar processing enzyme antibody, legumain antibody, legumain L homeolog antibody, delta vacuolar processing enzyme antibody, Legumain antibody, LGMN antibody, Lgmn antibody, lgmn.L antibody, lgmn antibody, DELTA-VPE antibody, MBOO_RS07785 antibody, Odosp_3582 antibody, LOC569153 antibody

Background: Full Gene Name: legumain
Synonyms: AEP,LGMN1,PRSC1

Gene ID: 5641

Pathways: Metabolism of Steroid Hormones and Vitamin D, Activation of Innate immune Response, Toll-Like Receptors Cascades