PPOX antibody (AA 378-477)

Catalog No. ABIN562343

Product Details anti-PPOX Antibody

Target: PPOX (Protoporphyrinogen Oxidase (PPOX))

Binding Specificity: AA 378-477

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PPOX antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi)

Purpose: Mouse monoclonal antibody raised against a partial recombinant PPOX.

Sequence: EASGCVLSQE LFQQRAQEAA ATQLGLKEMP SHCLVHLHKN CIPQYTLGHW QKLESARQFL TAHRLPLTLA GASYEGVAVN DCIESGRQAA VSVLGTEPNS

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: PPOX (AAH02357, 378 a.a. ~ 477 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 2F10

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-PPOX antibody (ABIN562343)

Yang, Chen, Chiang, Huang, Lee, Liu, Chang, Hsu: "Improve efficacy of topical ALA-PDT by calcipotriol through up-regulation of coproporphyrinogen oxidase." in: Photodiagnosis and photodynamic therapy, Vol. 11, Issue 3, pp. 331-41, (2014) (PubMed).

Yang, Lee, Chen, Huang, Hsu: "Methotrexate enhances 5-aminolevulinic acid-mediated photodynamic therapy-induced killing of human SCC4 cells by upregulation of coproporphyrinogen oxidase." in: Journal of the Formosan Medical Association = Taiwan yi zhi, Vol. 113, Issue 2, pp. 88-93, (2014) (PubMed).

Crooks, Ghosh, Haller, Tong, Rouault: "Posttranslational stability of the heme biosynthetic enzyme ferrochelatase is dependent on iron availability and intact iron-sulfur cluster assembly machinery." in: Blood, Vol. 115, Issue 4, pp. 860-9, (2010) (PubMed).

Target Details for PPOX

Target: PPOX (Protoporphyrinogen Oxidase (PPOX))

Alternative Name: PPOX (PPOX Products)

Synonyms: PPO antibody, V290M antibody, VP antibody, Ppo antibody, BcDNA:LD41392 antibody, CG5796 antibody, Dmel\\CG5796 antibody, ESTS:9F2T antibody, zgc:123252 antibody, HEMG1 antibody, PPO1 antibody, PROTOPORPHYRINOGEN OXIDASE antibody, TC0121 antibody, hemG antibody, protoporphyrinogen oxidase antibody, Protoporphyrinogen oxidase antibody, Flavin containing amine oxidoreductase family antibody, polyphenol oxidase, chloroplastic antibody, PPOX antibody, Ppox antibody, ppox antibody, hemY antibody, TC_RS00645 antibody, Mrub_1406 antibody, Mesil_2992 antibody, Trad_0583 antibody, Calni_0746 antibody, Ocepr_1049 antibody, Tmar_0766 antibody, Intca_1907 antibody, Despr_0642 antibody, Plabr_2407 antibody, Deipr_2130 antibody, Hipma_0622 antibody, LOC110782963 antibody

Background: Full Gene Name: protoporphyrinogen oxidase
Synonyms: MGC8485,PPO,V290M,VP

Gene ID: 5498

Pathways: Synaptic Membrane, Feeding Behaviour