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Progesterone Receptor antibody (AA 1-110)

Name: Progesterone Receptor antibody (AA 1-110)
SKU: ABIN562204
Price: 651.43 USD
Availability: InStock

PGR Reactivity: Human WB, ELISA, IHC (p), IF Host: Mouse Monoclonal 5D10 unconjugated

Western Blot detection against Immunogen (37. (Progesterone Receptor antibody (AA 1-110))

Immunofluorescence of monoclonal antibody to PGR on MCF-7 cell. (Progesterone Receptor antibody (AA 1-110))

Detection limit for recombinant GST tagged PGR is approximately 0. (Progesterone Receptor antibody (AA 1-110))

ELISA

Immunoperoxidase of monoclonal antibody to PGR on formalin-fixed paraffin-embedded human breast cancer. (Progesterone Receptor antibody (AA 1-110))

IHC (fp)

ISt

5 images

(2 references)

Catalog No. ABIN562204

Datasheet as PDF

Target See all Progesterone Receptor (PGR) Antibodies

Progesterone Receptor (PGR)
Binding Specificity
16

15

15

14

14

12

11

10

10

8

8

8

7

7

7

7

6

6

5

5

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-110
Reactivity
246

46

43

16

15

8

6

6

5

3

3

2

1

1

1

1

1
Human
Host
188

61

1

1
Mouse
Compatible Secondaries
Clonality
185

66
Monoclonal
Conjugate
122

21

11

11

8

7

6

6

6

6

6

6

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1
This Progesterone Receptor antibody is un-conjugated
Application
177

89

60

31

28

26

26

22

18

18

17

10

6

3

2

1

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purpose

Mouse monoclonal antibody raised against a partial recombinant PGR. This PGR gene uses two distinct promoters and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B. Our immunogen corresponds to the specific region of isoform B, thus this antibody is a PGR isofrom B specific antibody.

Sequence

MTELKAKGPR APHVAGGPPS PEVGSPLLCR PAAGPFPGSQ TSDTLPEVSA IPISLDGLLF PRPCQGQDPS DEKTQDQQSL SDVEGAYSRA EATRGAGGSS SSPPEKDSGL

Cross-Reactivity

Human, Rat

Characteristics

Antibody Reactive Against Recombinant Protein.

Immunogen

PGR (NP_000917, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone

5D10

Isotype

IgG1

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PGR Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated

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PGR Reactivity: Human, Monkey WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

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PGR Reactivity: Human, Rat, Mouse, Monkey WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

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PGR Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated

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PGR Reactivity: Human IHC, StM Host: Mouse Monoclonal PGR-2694 unconjugated

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Buffer

In 1x PBS, pH 7.4

Handling Advice

Aliquot to avoid repeated freezing and thawing.

Storage

-20 °C

Storage Comment

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Liu, Chang, Kuo, Hwa, Lin, Huang, Chen, Chang, Hsieh: "Major Functional Transcriptome of an Inferred Center Regulator of an ER(-) Breast Cancer Model System." in: Cancer informatics, Vol. 11, pp. 87-111, (2012) (PubMed).

Liu, Chang, Kuo, Hwa, Shyu, Chang, Hsieh: "In Silico Prediction for Regulation of Transcription Factors onTheir Shared Target Genes Indicates Relevant Clinical Implications in a Breast Cancer Population." in: Cancer informatics, Vol. 11, pp. 113-37, (2012) (PubMed).
Target

Progesterone Receptor (PGR)

Alternative Name

PGR (PGR Products)

Synonyms

NR3C3 antibody, PR antibody, 9930019P03Rik antibody, BB114106 antibody, ENSMUSG00000074510 antibody, PR-A antibody, PR-B antibody, XPR-1 antibody, pgr antibody, xpr-2 antibody, LOC443444 antibody, PGR antibody, pg antibody, pr antibody, gb:dq017620 antibody, progesterone receptor antibody, progesterone receptor L homeolog antibody, PGR antibody, Pgr antibody, pgr.L antibody, pgr antibody

Background

Full Gene Name: progesterone receptor
Synonyms: NR3C3,PR

Gene ID

5241

NCBI Accession

NM_000926

Pathways

Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration