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PDK2 antibody (AA 187-276)

Name: PDK2 antibody (AA 187-276)
SKU: ABIN562160
Price: 651.43 USD
Availability: InStock

PDK2 Reactivity: Human WB, ELISA, IHC (p), RNAi Host: Mouse Monoclonal 2G1 unconjugated

PDK2 monoclonal antibody (M01), clone 2G1 Western Blot analysis of PDK2 expression in U-2 OS . (PDK2 antibody (AA 187-276))

Western blot analysis of PDK2 over-expressed 293 cell line, cotransfected with PDK2 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). (PDK2 antibody (AA 187-276))

Immunoperoxidase of monoclonal antibody to PDK2 on formalin-fixed paraffin-embedded human salivary gland. (PDK2 antibody (AA 187-276))

ISt

Detection limit for recombinant GST tagged PDK2 is approximately 0. (PDK2 antibody (AA 187-276))

ELISA

Western Blot analysis of PDK2 expression in transfected 293T cell line by PDK2 monoclonal antibody (M01), clone 2G1. (PDK2 antibody (AA 187-276))

Western Blot detection against Immunogen (35. (PDK2 antibody (AA 187-276))

6 images

(4 references)

Catalog No. ABIN562160

Datasheet as PDF

Target See all PDK2 Antibodies

PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))
Binding Specificity
15

10

8

7

7

6

3

3

2

2

2

2

1

1

1

1

1

1

1

1
AA 187-276
Reactivity
87

53

45

8

3

2

2

1

1

1

1

1

1

1
Human
Host
81

13
Mouse
Compatible Secondaries
Clonality
76

18
Monoclonal
Conjugate
41

8

6

6

5

5

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
This PDK2 antibody is un-conjugated
Application
78

48

39

16

14

13

10

6

3

2

2

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi)

Purpose

Mouse monoclonal antibody raised against a partial recombinant PDK2.

Sequence

HIGSIDPNCN VSEVVKDAYD MAKLLCDKYY MASPDLEIQE INAANSKQPI HMVYVPSHLY HMLFELFKNA MRATVESHES SLILPPIKVM

Cross-Reactivity

Human

Characteristics

Antibody Reactive Against Recombinant Protein.

Immunogen

PDK2 (AAH05811, 187 a.a. ~ 276 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone

2G1

Isotype

IgG2a
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 155-379) antibody
PDK2 Reactivity: Mouse WB, IHC, ICC, IP Host: Rabbit Polyclonal unconjugated

anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 178-404) antibody
PDK2 Reactivity: Human WB, ELISA, FACS Host: Mouse Monoclonal 3F2D7 unconjugated

anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (C-Term) antibody
PDK2 Reactivity: Human, Mouse, Rat WB, IHC (p), ICC Host: Rabbit Polyclonal unconjugated

anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 378-407), (C-Term) antibody
PDK2 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB03037 unconjugated

anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) antibody
PDK2 Reactivity: Human WB, IHC (p), FACS Host: Rabbit Polyclonal RB23089 unconjugated

anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 78-107), (N-Term) antibody
PDK2 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB34663 unconjugated

anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 128-407) antibody
PDK2 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated

anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 128-407) antibody
PDK2 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated

anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 379-392), (C-Term) antibody
PDK2 Reactivity: Human, Rat WB, IHC (p), ICC Host: Rabbit Polyclonal unconjugated

anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (Internal Region) antibody
PDK2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, ICC, IF Host: Rabbit Polyclonal unconjugated

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Buffer

In 1x PBS, pH 7.4

Handling Advice

Aliquot to avoid repeated freezing and thawing.

Storage

-20 °C

Storage Comment

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Gannon, Ables, Crawford, Lowe, Offield, Magnuson, Wright: "pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis." in: Developmental biology, Vol. 314, Issue 2, pp. 406-17, (2008) (PubMed).

Babu, Deering, Mirmira: "A feat of metabolic proportions: Pdx1 orchestrates islet development and function in the maintenance of glucose homeostasis." in: Molecular genetics and metabolism, Vol. 92, Issue 1-2, pp. 43-55, (2007) (PubMed).

Gu, Dubauskaite, Melton: "Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors." in: Development (Cambridge, England), Vol. 129, Issue 10, pp. 2447-57, (2002) (PubMed).

Ohlsson, Karlsson, Edlund: "IPF1, a homeodomain-containing transactivator of the insulin gene." in: The EMBO journal, Vol. 12, Issue 11, pp. 4251-9, (1993) (PubMed).
Target

PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))

Alternative Name

PDK2 (PDK2 Products)

Synonyms

PDHK2 antibody, PDKII antibody, Pdk antibody, zgc:56209 antibody, PDK2 antibody, pyruvate dehydrogenase kinase 2 antibody, pyruvate dehydrogenase kinase, isoenzyme 2 antibody, pyruvate dehydrogenase kinase, isozyme 2b antibody, PDK2 antibody, Pdk2 antibody, pdk2b antibody

Background

Full Gene Name: pyruvate dehydrogenase kinase, isozyme 2
Synonyms: PDHK2

Gene ID

5164

Pathways

PI3K-Akt Signaling, RTK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect