PCBP2 antibody (AA 1-362)

Catalog No. ABIN562121

Product Details anti-PCBP2 Antibody

Target: PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))

Binding Specificity: AA 1-362

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PCBP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi)

Purpose: Mouse monoclonal antibody raised against a full length recombinant PCBP2.

Sequence: MDTGVIEGGL NVTLTIRLLM HGKEVGSIIG KKGESVKKMR EESGARINIS EGNCPERIIT LAGPTNAIFK AFAMIIDKLE EDISSSMTNS TAASRPPVTL RLVVPASQCG SLIGKGGCKI KEIRESTGAQ VQVAGDMLPN STERAITIAG IPQSIIECVK QICVVMLESP PKGVTIPYRP KPSSSPVIFA GGQDRYSTGS DSASFPHTTP SMCLNPDLEG PPLEAYTIQG QYAIPQPDLT KLHQLAMQQS HFPMTHGNTG FSGIESSSPE VKGYWAGLDA SAQTTSHELT IPNDLIGCII GRQGAKINEI RQMSGAQIKI ANPVEGSTDR QVTITGSAAS ISLAQYLINV RLSSETGGMG SS

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: PCBP2 (AAH01155, 1 a.a. ~ 362 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 5F12

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-PCBP2 antibody (ABIN562121)

Yanatori, Richardson, Imada, Kishi: "Iron Export through the Transporter Ferroportin 1 Is Modulated by the Iron Chaperone PCBP2." in: The Journal of biological chemistry, Vol. 291, Issue 33, pp. 17303-18, (2016) (PubMed).

Li, Masaki, Shimakami, Lemon: "hnRNP L and NF90 interact with hepatitis C virus 5'-terminal untranslated RNA and promote efficient replication." in: Journal of virology, Vol. 88, Issue 13, pp. 7199-209, (2014) (PubMed).

Fujimura, Sasaki, Anderson: "Selenite targets eIF4E-binding protein-1 to inhibit translation initiation and induce the assembly of non-canonical stress granules." in: Nucleic acids research, Vol. 40, Issue 16, pp. 8099-110, (2012) (PubMed).

Wang, Jeng, Lai et al.: "Poly(C)-binding protein 2 interacts with sequences required for viral replication in the hepatitis C virus (HCV) 5' untranslated region and directs HCV RNA replication through circularizing the viral ..." in: Journal of virology, Vol. 85, Issue 16, pp. 7954-64, (2011) (PubMed).

Süss, Czupalla, Winter, Pursche, Knoch, Schroeder, Hoflack, Solimena: "Rapid changes of mRNA-binding protein levels following glucose and 3-isobutyl-1-methylxanthine stimulation of insulinoma INS-1 cells." in: Molecular & cellular proteomics : MCP, Vol. 8, Issue 3, pp. 393-408, (2009) (PubMed).

Fujimura, Katahira, Kano, Yoneda, Murata: "Selective localization of PCBP2 to cytoplasmic processing bodies." in: Biochimica et biophysica acta, Vol. 1793, Issue 5, pp. 878-87, (2009) (PubMed).

Lawrence, Rieder: "Identification of RNA helicase A as a new host factor in the replication cycle of foot-and-mouth disease virus." in: Journal of virology, Vol. 83, Issue 21, pp. 11356-66, (2009) (PubMed).

Fujimura, Kano, Murata: "Identification of PCBP2, a facilitator of IRES-mediated translation, as a novel constituent of stress granules and processing bodies." in: RNA (New York, N.Y.), Vol. 14, Issue 3, pp. 425-31, (2008) (PubMed).

Ghosh, Srivastava, Xu, Schulz, Roberts: "A link between SIN1 (MAPKAP1) and poly(rC) binding protein 2 (PCBP2) in counteracting environmental stress." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 33, pp. 11673-8, (2008) (PubMed).

Target Details for PCBP2

Target: PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))

Alternative Name: PCBP2 (PCBP2 Products)

Synonyms: HNRNPE2 antibody, HNRPE2 antibody, hnRNP-E2 antibody, AW412548 antibody, Hnrpx antibody, alphaCP-2 antibody, PCBP3 antibody, fb36h02 antibody, wu:fb36h02 antibody, zgc:55964 antibody, PCBP2 antibody, poly(rC) binding protein 2 antibody, poly(rC) binding protein 2 L homeolog antibody, PCBP2 antibody, Pcbp2 antibody, pcbp2 antibody, pcbp2.L antibody

Background: Full Gene Name: poly(rC) binding protein 2
Synonyms: HNRPE2,MGC110998,hnRNP-E2

Gene ID: 5094