NOTCH3
Reactivity: Human
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Buffer
In 1x PBS, pH 7.4
Handling Advice
Aliquot to avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Meng, Zhang, Lee, Wang: "Von Willebrand factor inhibits mature smooth muscle gene expression through impairment of Notch signaling." in: PLoS ONE, Vol. 8, Issue 9, pp. e75808, (2013) (PubMed).
Watanabe-Hosomi, Watanabe, Tanaka, Nakagawa, Mizuno: "Transendocytosis is impaired in CADASIL-mutant NOTCH3." in: Experimental neurology, Vol. 233, Issue 1, pp. 303-11, (2012) (PubMed).
Tada, Itoh, Ishii-Watabe, Suzuki, Kawasaki: "Functional analysis of the Notch ligand Jagged1 missense mutant proteins underlying Alagille syndrome." in: The FEBS journal, Vol. 279, Issue 12, pp. 2096-107, (2012) (PubMed).
Dong, Blaivas, Wang: "Bidirectional encroachment of collagen into the tunica media in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy." in: Brain research, Vol. 1456, pp. 64-71, (2012) (PubMed).
Lee, Meng, Elmadhoun, Blaivas, Wang: "Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy affecting an African American man: identification of a novel 15-base pair NOTCH3 duplication." in: Archives of neurology, Vol. 68, Issue 12, pp. 1584-6, (2011) (PubMed).
Meng, Zhang, Hankenson, Wang: "Thrombospondin 2 potentiates notch3/jagged1 signaling." in: The Journal of biological chemistry, Vol. 284, Issue 12, pp. 7866-74, (2009) (PubMed).
Park, Shih, Wang: "Identification of Pbx1, a potential oncogene, as a Notch3 target gene in ovarian cancer." in: Cancer research, Vol. 68, Issue 21, pp. 8852-60, (2008) (PubMed).