LOXL2 antibody (AA 675-773)

Catalog No. ABIN561690

Product Details anti-LOXL2 Antibody

Target: LOXL2 (Lysyl Oxidase-Like 2 (LOXL2))

Binding Specificity: AA 675-773

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LOXL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Mouse monoclonal antibody raised against a partial recombinant LOXL2.

Sequence: NFGDQGITMG CWDMYRHDID CQWVDITDVP PGDYLFQVVI NPNFEVAESD YSNNIMKCRS RYDGHRIWMY NCHIGGSFSE ETEKKFEHFS GLLNNQLSP

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: LOXL2 (NP_002309, 675 a.a. ~ 773 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 5D2

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-LOXL2 antibody (ABIN561690)

Li, Xu, Wu, Liao, Shen, Xu, Du, Zhao, Li: "Reduced nuclear and ectopic cytoplasmic expression of lysyl oxidase-like 2 is associated with lymph node metastasis and poor prognosis in esophageal squamous cell carcinoma." in: Human pathology, Vol. 43, Issue 7, pp. 1068-76, (2012) (PubMed).

Li, Li, Cheng, Wu, Gao, Liu, Jiang, Gao, Tian, Zhao, Wang: "Epithelial-mesenchymal transition induced by hepatitis C virus core protein in cholangiocarcinoma." in: Annals of surgical oncology, Vol. 17, Issue 7, pp. 1937-44, (2010) (PubMed).

Fujimoto, Tajima: "Reciprocal regulation of LOX and LOXL2 expression during cell adhesion and terminal differentiation in epidermal keratinocytes." in: Journal of dermatological science, Vol. 55, Issue 2, pp. 91-8, (2009) (PubMed).

Target Details for LOXL2

Target: LOXL2 (Lysyl Oxidase-Like 2 (LOXL2))

Alternative Name: LOXL2 (LOXL2 Products)

Background: Full Gene Name: lysyl oxidase-like 2
Synonyms: LOR2,WS9-14

Gene ID: 4017

NCBI Accession: NM_002318

Pathways: Chromatin Binding