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HSD17B1 antibody (AA 189-285)

HSD17B1 Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 2E5 unconjugated
Catalog No. ABIN561371
  • Target See all HSD17B1 Antibodies
    HSD17B1 (Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1))
    Binding Specificity
    • 9
    • 9
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    AA 189-285
    Reactivity
    • 62
    • 20
    • 20
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 63
    • 1
    • 1
    Mouse
    Clonality
    • 64
    • 1
    Monoclonal
    Conjugate
    • 22
    • 8
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HSD17B1 antibody is un-conjugated
    Application
    • 45
    • 23
    • 13
    • 8
    • 8
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purpose
    Mouse monoclonal antibody raised against a partial recombinant HSD17B1.
    Sequence
    VHTAFMEKVL GSPEEVLDRT DIHTFHRFYQ YLAHSKQVFR EAAQNPEEVA EVFLTALRAP KPTLRYFTTE RFLPLLRMRL DDPSGSNYVT AMHREVF
    Cross-Reactivity
    Human
    Characteristics
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    HSD17B1 (NP_000404, 189 a.a. ~ 285 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    2E5
    Isotype
    IgG1
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • McNamara, Oguro, Omata, Kikuchi, Guestini, Suzuki, Yang, Abe, Hirakawa, Brown, Takanori, Ohuchi, Sasano: "The presence and impact of estrogen metabolism on the biology of triple-negative breast cancer." in: Breast cancer research and treatment, Vol. 161, Issue 2, pp. 213-227, (2016) (PubMed).

    Inoue, Miki, Abe, Hatori, Hosaka, Kariya, Kakuo, Fujimura, Hachiya, Aiba, Sasano: "The role of estrogen-metabolizing enzymes and estrogen receptors in human epidermis." in: Molecular and cellular endocrinology, Vol. 344, Issue 1-2, pp. 35-40, (2011) (PubMed).

    Chanplakorn, Chanplakorn, Suzuki, Ono, Chan, Miki, Saji, Ueno, Toi, Sasano: "Increased estrogen sulfatase (STS) and 17beta-hydroxysteroid dehydrogenase type 1(17beta-HSD1) following neoadjuvant aromatase inhibitor therapy in breast cancer patients." in: Breast cancer research and treatment, Vol. 120, Issue 3, pp. 639-48, (2010) (PubMed).

  • Target
    HSD17B1 (Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1))
    Alternative Name
    HSD17B1 (HSD17B1 Products)
    Synonyms
    EDH17B2 antibody, EDHB17 antibody, HSD17 antibody, SDR28C1 antibody, 17HSDB1 antibody, 17beta-HSD antibody, E2DH antibody, Hsd17ba antibody, 17BHD1 antibody, zfHSD17B1 antibody, hydroxysteroid 17-beta dehydrogenase 1 antibody, hydroxysteroid (17-beta) dehydrogenase 1 antibody, HSD17B1 antibody, Hsd17b1 antibody, hsd17b1 antibody
    Background
    Full Gene Name: hydroxysteroid (17-beta) dehydrogenase 1
    Synonyms: EDH17B2,EDHB17,HSD17,MGC138140,SDR28C1
    Gene ID
    3292
    NCBI Accession
    NM_000413
    Pathways
    Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis
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