CHRND antibody (AA 22-245)

Catalog No. ABIN5611361

Product Details anti-CHRND Antibody

Target: CHRND (Cholinergic Receptor, Nicotinic, delta (Muscle) (CHRND))

Binding Specificity: AA 22-245

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CHRND antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purpose: CHRND Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CHRND (AA: 22-245) expressed in E. Coli.

Clone: 1H1F9

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for CHRND

Target: CHRND (Cholinergic Receptor, Nicotinic, delta (Muscle) (CHRND))

Alternative Name: CHRND (CHRND Products)

Background:

Description: The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in this gene are a cause of multiple pterygium syndrome lethal type (MUPSL), congenital myasthenic syndrome slow-channel type (SCCMS), and congenital myasthenic syndrome fast-channel type (FCCMS). Several transcript variants encoding different isoforms have been found for this gene.

Aliases: ACHRD, CMS2A, CMS3A, CMS3B, CMS3C, FCCMS, SCCMS

Molecular Weight: 58.8kDa

Gene ID: 1144

HGNC: 1144

UniProt: Q07001