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ATRX antibody (AA 2311-2492)

ATRX Reactivity: Human ELISA, WB, IHC, FACS, ICC, Neut Host: Mouse Monoclonal 8B2H9 unconjugated
Catalog No. ABIN5611354
  • Target See all ATRX Antibodies
    ATRX (helicase 2, X-linked (ATRX))
    Binding Specificity
    • 13
    • 6
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2311-2492
    Reactivity
    • 57
    • 16
    • 3
    • 3
    • 2
    • 2
    Human
    Host
    • 39
    • 20
    • 1
    Mouse
    Clonality
    • 36
    • 24
    Monoclonal
    Conjugate
    • 35
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATRX antibody is un-conjugated
    Application
    • 35
    • 26
    • 20
    • 16
    • 15
    • 11
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human ATRX (AA: 2311-2492) expressed in E. coli.
    Clone
    8B2H9
    Isotype
    IgG1
    Top Product
    Discover our top product ATRX Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: N/A, IHC: N/A
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Target
    ATRX (helicase 2, X-linked (ATRX))
    Alternative Name
    ATRX (ATRX Products)
    Synonyms
    ATR2 antibody, JMS antibody, MRXHF1 antibody, RAD54 antibody, RAD54L antibody, SFM1 antibody, SHS antibody, XH2 antibody, XNP antibody, ZNF-HX antibody, 4833408C14Rik antibody, AI447451 antibody, DXHXS6677E antibody, HP1-BP38 antibody, Hp1bp2 antibody, Hp1bp38 antibody, MRXS3 antibody, Rad54 antibody, Xnp antibody, atrx antibody, rad54 antibody, atrxl antibody, wu:fb26e12 antibody, wu:fb52h08 antibody, wu:fb72g09 antibody, wu:fb94e07 antibody, zgc:66223 antibody, ATRX, chromatin remodeler antibody, alpha thalassemia/mental retardation syndrome X-linked L homeolog antibody, alpha thalassemia/mental retardation syndrome X-linked homolog (human) antibody, ATRX antibody, Atrx antibody, atrx.L antibody, atrx antibody
    Background

    Description: The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Mutations in this gene are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

    Aliases: JMS, SHS, XH2, XNP, ATR2, SFM1, MRX52, RAD54, MRXHF1, RAD54L, ZNF-HX

    Molecular Weight
    282.5 kDa
    Gene ID
    546
    HGNC
    546
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