ATG4C antibody (AA 321-458)

Catalog No. ABIN5611292

Product Details anti-ATG4C Antibody

Target: ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))

Binding Specificity: AA 321-458

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ATG4C antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: ATG4C Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human ATG4C (AA: 321-458) expressed in E. Coli.

Clone: 2E10H7

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for ATG4C

Target: ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))

Alternative Name: ATG4C (ATG4C Products)

Background:

Description: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized.

Aliases: APG4C, AUTL1, AUTL3, APG4-C

Molecular Weight: 52.5kDa

Gene ID: 84938

HGNC: 84938

UniProt: Q96DT6

Pathways: Autophagy