RUNX3 antibody (AA 294-429)

Catalog No. ABIN5611279

Product Details anti-RUNX3 Antibody

Target: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Binding Specificity: AA 294-429

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RUNX3 antibody is un-conjugated

Application: ELISA

Purpose: RUNX3 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human RUNX3 (AA: 294-429) expressed in E. Coli.

Clone: 8C9B6

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for RUNX3

Target: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Alternative Name: RUNX3 (RUNX3 Products)

Background:

Description: This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants.

Aliases: AML2, CBFA3, PEBP2aC

Molecular Weight: 44.4kDa

Gene ID: 864

HGNC: 864

UniProt: Q13761