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DC-SIGN/CD209 antibody (AA 270-404)

CD209 Reactivity: Human WB, FACS, ELISA Host: Mouse Monoclonal 5C2A6 unconjugated
Catalog No. ABIN5611274
  • Target See all DC-SIGN/CD209 (CD209) Antibodies
    DC-SIGN/CD209 (CD209) (CD209)
    Binding Specificity
    • 8
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 270-404
    Reactivity
    • 99
    • 27
    • 22
    • 1
    • 1
    Human
    Host
    • 75
    • 37
    • 4
    • 1
    Mouse
    Clonality
    • 74
    • 43
    Monoclonal
    Conjugate
    • 57
    • 9
    • 8
    • 6
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DC-SIGN/CD209 antibody is un-conjugated
    Application
    • 71
    • 43
    • 32
    • 31
    • 25
    • 13
    • 6
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), ELISA
    Purpose
    CD209 Antibody
    Purification
    Purified antibody
    Immunogen
    Purified recombinant fragment of human CD209 (AA: 270-404) expressed in E. Coli.
    Clone
    5C2A6
    Isotype
    IgG1
    Top Product
    Discover our top product CD209 Primary Antibody
  • Application Notes

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    DC-SIGN/CD209 (CD209) (CD209)
    Alternative Name
    CD209 (CD209 Products)
    Synonyms
    CDSIGN antibody, CLEC4L antibody, DC-SIGN antibody, DC-SIGN1 antibody, cd209 antibody, CLEC4M antibody, si:ch211-224h1.3 antibody, CD209 antibody, CIRE antibody, Dcsign antibody, SIGN-R1 antibody, SIGNR5 antibody, Cd209 antibody, CD209 molecule antibody, CD209a antigen antibody, CD209 antigen-like protein D antibody, CD209c molecule antibody, CD209 antigen antibody, CD209 antibody, cd209 antibody, Cd209a antibody, LOC100529184 antibody, Cd209c antibody, LOC100460708 antibody, LOC105484282 antibody
    Background

    Description: This gene encodes a transmembrane receptor and is often referred to as DC-SIGN because of its expression on the surface of dendritic cells and macrophages. The encoded protein is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses with a large impact on public health. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. Variations in the number of 23 amino acid repeats in the neck domain of this protein are rare but have a significant impact on ligand binding ability. This gene is closely related in terms of both sequence and function to a neighboring gene (GeneID 10332, often referred to as L-SIGN). DC-SIGN and L-SIGN differ in their ligand-binding properties and distribution. Alternative splicing results in multiple variants.

    Aliases: CDSIGN, CLEC4L, DC-SIGN, DC-SIGN1

    Molecular Weight
    45.8kDa
    Gene ID
    30835
    HGNC
    30835
    UniProt
    Q9NNX6
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